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TranscriptomicsPerivascular Human Endometrial Mesenchymal Stem Cells Express Pathways Relevant to Self-Renewal, Lineage Specification, and Functional Phenotype
A population of endometrial cells displaying key properties of mesenchymal stem cells (eMSC) has been identified in human endometrium. eMSC co-express CD146 and PDGFRB surface markers, have a perivascular location, and likely represent the reservoir of progenitors giving rise to the endometrial str...
ORGANISM(S): Homo sapiens 
2011-11-14 | E-GEOD-31152 | biostudies-arrayexpress
TranscriptomicsNovel isolation strategy to deliver pure fetal-origin and maternal- origin mesenchymal stem cell (MSC) populations from human term placenta
The placenta is an abundant source of mesenchymal stem/stromal cells (MSC). Although presumed of translationally-advantageous fetal origin, the literature instead suggests a high incidence of either contaminating or pure maternal MSC. Despite definitional criteria that MSC are CD34ÌÛ, increasing evi...
ORGANISM(S): Homo sapiens 
2018-12-01 | E-MTAB-3229 | biostudies-arrayexpress
TranscriptomicsGenome wide expression profiling of mesenchymal stem cells of fetal and adult origin and dermal fibroblasts
In animal models and human trials, intramyocardial injection of adult bone-marrow derived mesenchymal stem cells (BM-MSC) provides beneficial effects in failing hearts. These effects are mainly mediated through paracrine mechanisms. Mesenchymal stem cells of fetal origin (hAMC) can be isolated from ...
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-61153 | biostudies-arrayexpress
ProteomicsPriming-Dependent Modulation of Secretome in Placenta- and Adipose-Derived Mesenchymal Stromal/Stem cells: Toward Cell-Free Immunoregenerative Therapies for Osteoarticular Disorders
Age-related bone degeneration is driven by structural deterioration, chronic inflammation, and impaired regenerative capacity, leading to an increased incidence of osteoarticular disorders. Mesenchymal stromal/stem cells (MSCs) have emerged as promising therapeutic candidates due to their immunomodu...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD068866 | Pride
Placenta-derived mscs Exosomal microrna Mesenchymal stromal cells Cytokine priming Adipose-derived mscs Secretome Proteomics Extracellular vesicles Osteogenesis Chondrogenesis 
TranscriptomicsTranscription profiling by array of week by week changes in the transcriptional ontogeny of first trimester human fetal mesenchymal stem cells
We characterized the developmental transciptome of first trimester MSC from fetal bone marrow (BM) compared to that from adnexal structures across multiple time points (8wks-12wks). Please note: DevelopmentalStage (Early =weeks 8-9, Late = weeks 10-12)
ORGANISM(S): Homo sapiens 
2014-11-24 | E-TABM-1224 | biostudies-arrayexpress
UnknownIntegrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mesenchymal Stem/Stromal Cells Derived from Human Placenta.
Not available
S-EPMC9017713 | biostudies-literature
ProteomicsProteomic analysis and functional validation reveal distinct therapeutic capabilities related to priming of mesenchymal stromal/stem cells with IFN-γ and hypoxia: potential implications for their clinical use
Mesenchymal stromal/stem cells (MSCs) are a heterogeneous population of multipotent cells that can be obtained from various tissues, such as dental pulp, adipose tissue, bone marrow and placenta. MSCs have gained importance in the field of regenerative medicine because of their promising role in cel...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD052445 | Pride
Msc priming Msc therapeutic properties Proteomic analysis Msc paracrine effects Placenta-derived mesenchymal stromal/stem cells Ifn-γ priming Hypoxia priming 
UnknownCan Human Embryonic Stem Cell-Derived Stromal Cells Serve a Starting Material for Myoblasts?
Not available
S-EPMC5494578 | biostudies-literature
UnknownComparison of the Biological Characteristics of Mesenchymal Stem Cells Derived from the Human Placenta and Umbilical Cord.
Not available
S-EPMC5864926 | biostudies-literature
UnknownTranscriptomic portrait of human Mesenchymal Stromal/Stem Cells isolated from bone marrow and placenta.
Not available
S-EPMC4287589 | biostudies-literature
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