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TranscriptomicsCLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 13]
Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cell...
ORGANISM(S): Homo sapiens 
2015-08-31 | E-GEOD-70994 | biostudies-arrayexpress
TranscriptomicsCLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 15]
Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cell...
ORGANISM(S): Homo sapiens 
2015-08-31 | E-GEOD-70995 | biostudies-arrayexpress
ProteomicsProteome profiling of blood plasma-derived exosomes in chronic lymphocytic leukemia
In order to analyze differences in the proteome composition of blood plasma-derived exosomes in chronic lymphocytic leukemia (CLL) versus healthy donors, mass spectrometry was conducted for whole protein lysates of plasma-derived exosomes. Abundance of proteins was compared via label free quantifica...
ORGANISM(S): Homo sapiens (Human) 
2017-08-09 | PXD004420 | Pride
Extracellular vesicles Microvesicles Mass spectrometry Maxquant Cll Tumor microenvironment Chronic lymphocytic leukemia 
ProteomicsCLL exosomes - S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression
CLL exosomes purification during disease evolution from different patients
ORGANISM(S): Homo sapiens (Human) 
2017-06-19 | PXD005941 | Pride
Plasma-derived exosomes cll 
GenomicsSmall RNA sequencing of blood plasma-derived exosomes from CLL - samples
Small RNA expression profiles of the blood plasma-derived exosomes from B-cell chronic lymphocytic leukemia patients
EGAD00001003230 | EGA
GenomicsTumor-derived exosomes modulate PD-L1 expression in monocytes
In chronic lymphocytic leukemia (CLL), monocytes and macrophages are skewed toward protumorigenic phenotypes, including the release of tumor-supportive cytokines and the expression of immunosuppressive molecules such as programmed cell death 1 ligand 1 (PD-L1). To understand the mechanism driving pr...
EGAS00001002377 | EGA
GenomicsCLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 15]
Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cell...
ORGANISM(S): JC polyomavirus Betapolyomavirus hominis Homo sapiens Macacine alphaherpesvirus 1 Human betaherpesvirus 5 Human immunodeficiency virus 1 Merkel cell polyomavirus Herpesvirus saimiri (strain 11) Human gammaherpesvirus 8 Human alphaherpesvirus 1 Human alphaherpesvirus 2 human gammaherpesvirus 4 Human betaherpesvirus 6B Betapolyomavirus macacae 
2015-08-31 | GSE70995 | GEO
GenomicsCLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 13]
Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cell...
ORGANISM(S): Human alphaherpesvirus 2 Betapolyomavirus hominis Homo sapiens Macacine alphaherpesvirus 1 Merkel cell polyomavirus Human alphaherpesvirus 1 Human betaherpesvirus 5 human gammaherpesvirus 4 Human betaherpesvirus 6B Betapolyomavirus macacae Herpesvirus saimiri (strain 11) JC polyomavirus Human immunodeficiency virus 1 Human gammaherpesvirus 8 
2015-08-31 | GSE70994 | GEO
UnknownCharacterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling.
Not available
S-EPMC4440883 | biostudies-literature
UnknownCLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p.
Not available
S-EPMC4625016 | biostudies-literature
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