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RNA-seq of human platelets and platelet derived extracellular vesicles (EV)
To characterize proteomic signatures of platelet-derived medium-size EVs(mEVs) EVs of Colorectal cancer patients vs. healthy subjects (HS) matched for sex and age
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD038674 | Pride
Small RNA Landscape of Platelet Dust: Platelet-Derived Extracellular Vesicles from Patients with Non-Small-Cell Lung Cancer
Platelets and their extracellular vesicles (EVs) have emerged as promising liquid biopsy biosources for cancer detection and monitoring. The megakaryoblastic MEG-01 cell line offers a controlled system for generating platelet-like particles (PLPs) and EVs through valproic acid induced differentiatio...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD070221 | Pride
To determine the transcriptomic (mRNA and microRNA) content present in platelets and platelet derived extracellular vesicles (EV) we used RNA-Seq approach. The goal was to determine if the transcriptomic cargo carried by platelet derived extracellular vesicles is different than that of the fresh pla...
ORGANISM(S): Homo sapiens 
2026-07-20 | GSE262834 | GEO
Beyond Basic Characterization and Omics: Immunomodulatory Roles of Platelet-Derived Extracellular Vesicles Unveiled by Functional Testing
In blood banks, platelets are stored until 7 days after a pathogen reduction technology (PRT) treatment, Mirasol® (vitamin B2 plus UVB light) in the present case. The storage time under these conditions may have an impact on platelets and their releasate leading to potential adverse reactions follow...
ORGANISM(S): Homo sapiens (Human) 
2022-09-30 | PXD014694 | Pride
This study presents a comparative study of different methodologies for the extraction of proteins from platelet derived-extracellular vesicles (pEV) prior to subsequent mass spectrometry (MS) analysis. Protein isolation is performed through three different methodologies based on SDS-polyacrylamide g...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD060357 | Pride
Therapeutic effect of platelet-derived extracellular vesicles on viral myocarditis correlate with biomolecular content
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