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Briefly, we analyzed gene expression profiles in adherent cultures compared to sphere cultures from malignant pleural effusions (MPEs). MPEs could represent an opportunity to culture a wide variety of cancer cells from different donors. In this study, we set up culture conditions for cancer cells de...
ORGANISM(S): Homo sapiens 
Soluble HLA (sHLA) molecules released to the plasma, carry their original peptide cargo and provide insight into the protein synthesis and degradation schemes of their source cells and tissues. Other body fluids, such as pleural effusions, may also contain sHLA-peptide complexes, and can potentially...
ORGANISM(S): Homo sapiens (Human) 
2022-05-25 | PXD027766 | Pride
We screened pleural effusion proteomes of mesothelioma and lung adenocarcinoma patients to identify novel soluble mesothelioma biomarkers. We performed quantitative mass spectrometry-(MS-) based proteomics using isobaric tags for relative and absolute quantification (iTRAQ) and used narrow range imm...
ORGANISM(S): Homo sapiens (Human) 
2014-01-14 | PXD000531 | Pride
Expression of miRNA in exosomes from transudative pleural effusion and tuberculous pleural effusions
Cellular and Molecular Characterization of T cells in Malignant Pleural Effusions
Cellular and Molecular Characterization of T cells in Malignant Pleural Effusions
Cellular and Molecular Characterization of T cells in Malignant Pleural Effusions
RATIONALE: Using BG00001 to insert the gene for interferon-beta into a person’s pleural cavity may improve the body’s ability to fight cancer. PURPOSE: Phase I trial to study the effectiveness of intrapleural BG00001 in treating patients who have malignant pleural mesothelioma or malignant pleural e...
To decipher the heterogeneity and distinct molecular signatures of disseminated tumor cells, we profiled the transcriptomes single cells from malignant pleural effusion. RNA-seq was done using the standard 10x chromium v3 chemistry.
ORGANISM(S): Homo sapiens 
The cellular landscape of breast cancer associated malignant pleural effusions
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