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TranscriptomicsTranscriptomic analysis of germline tumor in fasted C. elegans
Transciptomic analysis of germline tumor cells to understand the role of autophagy and neuronal differentiation in lifespan extension. Methods: Worms were grown on control L444 seeded plates or gld-1 RNAi seeded plates and subjected to RNA isolation and sequencing using standard Illumina protocols. ...
ORGANISM(S): Caenorhabditis elegans 
2016-01-15 | E-GEOD-65406 | biostudies-arrayexpress
ProteomicsUbiquitin profiling of drug-like small molecule-treated cells
The ubiquitin system regulates eukaryotic physiology by modifying specific substrate proteins. Substrate recognition and the assembly of ubiquitin signals are determined by ubiquitin ligases, some of which also modify non-protein biomolecules. Here we expand this substrate realm, revealing that the ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-10 | PXD067088 | Pride
Drug-like small molecules Digly Ubiquitin Huwe1 
UnknownCrystalline and amorphous structure selectivity of ignoble high-entropy alloy nanoparticles during laser ablation in organic liquids is set by pulse duration.
Not available
S-EPMC12278108 | biostudies-literature
ProteomicsPAM complex sequesters from TIM translocon and becomes part of an insoluble protein fraction under protein folding stress
Upon mitochondrial dysfunction, mitophagy has been described to be activated by a breakdown of membrane potential leading to PINK1 accumulation on the outer membrane and engulfment of mitochondria for degradation. However, recent findings have indicated that mitophagy may also be triggered in the ab...
ORGANISM(S): Homo sapiens (Human) 
2022-09-03 | PXD022530 | Pride
Pam interactors Biotinylation-streptavidin-pull down Protein misfolding Turboid 
ProteomicsPAM complex sequesters from TIM translocon and becomes part of an insoluble protein fraction under protein folding stress
Upon mitochondrial dysfunction, mitophagy has been described to be activated by a breakdown of membrane potential leading to PINK1 accumulation on the outer membrane and engulfment of mitochondria for degradation. However, recent findings have indicated that mitophagy may also be triggered in the ab...
ORGANISM(S): Homo sapiens (Human) 
2022-09-03 | PXD022524 | Pride
Human Mitophagy Hela cell line Pam complex Lc-ms/ms 
ProteomicsProtein import defects induce mitophagy without membrane depolarization
Upon mitochondrial dysfunction, mitophagy has been described to be activated by a breakdown of membrane potential leading to PINK1 accumulation on the outer membrane and engulfment of mitochondria for degradation. However, recent findings have indicated that mitophagy may also be triggered in the ab...
ORGANISM(S): Homo sapiens (Human) 
2022-09-03 | PXD022560 | Pride
Mitophagy Protein misfolding Mitochondrial protein import Pulsed-silac 
UnknownLinking of sensor molecules with amino groups to amino-functionalized AFM tips.
Not available
S-EPMC3115690 | biostudies-literature
UnknownMutations in CDK5RAP2 cause Seckel syndrome.
Not available
S-EPMC4585455 | biostudies-literature
UnknownTransgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice.
Not available
S-EPMC7878873 | biostudies-literature
UnknownPatient's global assessment of disease activity and patient's assessment of general health for rheumatoid arthritis activity assessment: are they equivalent?
Not available
S-EPMC3731741 | biostudies-literature
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