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MetabolomicsCommon Metabolic Pathways Implicated in Resistance to Chemotherapy Point to a Key Mitochondrial Role in Breast Cancer
Cancer cells are known to reprogram their metabolism to adapt to adverse conditions dictated by tumor growth and microenvironment. A subtype of cancer cells with stem-like properties, known as cancer stem cells (CSC), is thought to be responsible for tumor recurrence. In this study, we demonstrated ...
2019-08-19 | MTBLS678 | MetaboLights
ProteomicsComparative proteomic analysis of hemolymph from uninfected and Candidatus Liberibacter asiaticus-infected Diaphorina citri
Hemolymph was characterized from Diaphorina citri adults infected with the phytopathogen, Candidatus Liberibacter asiaticus (CLas) and compared with that from uninfected psyllids. This study identified 5531 and 3220 peptides within infected and uninfected hemolymph using nano LC-MS/MS. A reduced num...
ORGANISM(S): Diaphorina citri (Asian citrus psyllid) Wolbachia endosymbiont of Diaphorina citri Candidatus Profftella armatura Liberibacter endosymbiont of Diaphorina citri Candidatus Carsonella ruddii DC 
2017-01-18 | PXD005404 | Pride
Asian citrus psyllid Hemolymph Diaphorina citri Endosymbionts Hemiptera 
TranscriptomicsRNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate
Pancreatic beta-cell dysfunction and death are central in the pathogenesis of type 2 diabetes. Saturated fatty acids cause beta-cell failure and contribute to diabetes development in genetically predisposed individuals. Here we used RNA-sequencing to map transcripts expressed in five palmitate-treat...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-53949 | biostudies-arrayexpress
ProteomicsProteomics of cassava storage roots before and after shoot pruning
Cassava (Manihot esculenta Crantz) is a food security crop for approximately 800 million people, primarily in developing economies. Cassava root yield is determined by the allocation of photoassimilated carbon within the plant, yet there is limited molecular and biochemical information about source-...
ORGANISM(S): Manihot esculenta (Cassava) (Jatropha manihot) 
2026-04-01 | PXD045690 | Pride
Manihot esculenta Storage roots Pruning Cassava 
MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
UnknownData on length of parathyroidectomy surgery and intraoperative parathyroid hormone (PTH) assay turnaround times following a switch in the location for intraoperative PTH testing from near point-of-care to central laboratory.
Not available
S-EPMC7486601 | biostudies-literature
UnknownEffect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial.
Not available
S-EPMC6583075 | biostudies-literature
TranscriptomicsMolecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival
Understanding the role of host factors during lethal influenza virus infection is critical to deciphering the events that will determine the fate of the host. One such factor is encoded by the Mx1 gene, which confers resistance to influenza virus infection. Here, we compared pathology and global gen...
ORGANISM(S): Mus musculus 
2012-02-20 | E-GEOD-35933 | biostudies-arrayexpress
Transcriptomicshourglass
The observation that animal morphology tends to be conserved during the embryonic phylotypic period led to the proposition that embryogenesis diverges more extensively early and late than in the middle, known as the hourglass model. This pattern of conservation is thought to reflect a major constrai...
ORGANISM(S): Drosophila simulans 
2011-02-18 | E-MTAB-404 | biostudies-arrayexpress
TranscriptomicsCorrelates of chronic stress and their influence on the development of substance use in a population-based cohort of young adults (OYSUP)
Background: We seek to understand correlates of chronic stress and their influence on the development of substance use in a population-based cohort of young adults (OYSUP). Methodology: We evaluated clinical features, salivary RNA metrics and differential expression of candidate genes in unfraction...
ORGANISM(S): Homo sapiens 
2012-06-15 | E-GEOD-27144 | biostudies-arrayexpress
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