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ProteomicsProteomics of cassava storage roots before and after shoot pruning
Cassava (Manihot esculenta Crantz) is a food security crop for approximately 800 million people, primarily in developing economies. Cassava root yield is determined by the allocation of photoassimilated carbon within the plant, yet there is limited molecular and biochemical information about source-...
ORGANISM(S): Manihot esculenta (Cassava) (Jatropha manihot) 
2026-04-01 | PXD045690 | Pride
Manihot esculenta Storage roots Pruning Cassava 
TranscriptomicsTranscription profiling of Drosophila mushroom body neurons at the onset and early steps of axon pruning
Drosophila mushroom body (MB) γ neurons undergo axon pruning during metamorphosis through a process of localized degeneration of specific axon branches. Developmental axon degeneration is initiated at the onset of metamorphosis by the pre-pupal rise in the steroid hormone ecdysone. This study ide...
ORGANISM(S): Drosophila melanogaster 
2008-06-18 | E-GEOD-10012 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila EcR-dependent gene expression in MB neurons at the onset of axon pruning
This study identifies genes that show EcR-dependent gene expression in MB neurons at the onset of axon pruning. Experiment Overall Design: A dominant negative form of the ecdysone receptor (EcRDN) was expressed in MB neurons by OK107-GAL4. Animals were staged at 0 and 5 hours relative to puparium f...
ORGANISM(S): Drosophila melanogaster 
2008-06-18 | E-GEOD-10013 | biostudies-arrayexpress
ProteomicsSmall intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning
Sepsis is a severe global health issue with high mortality rates, and sepsis-associated encephalopathy (SAE) further exacerbates this risk. While recent studies have shown the migration of gut immune cells to the lungs after sepsis, their impact on the central nervous system remains unclear. Our res...
ORGANISM(S): Mus Musculus 
2024-10-28 | PXD057241 |
TranscriptomicsTranscription profiling of Drosophila mushroom body neurons
Genomic analysis of axon pruning in Drosophila mushroom body neurons identifies the RNA-binding protein Boule as a negative regulator; This SuperSeries is composed of the following subset Series:; GSE10012: Timecourse: MB neurons at the onset and early steps of axon pruning; GSE10013: EcR-dependent ...
ORGANISM(S): Drosophila melanogaster 
2008-06-18 | E-GEOD-10014 | biostudies-arrayexpress
GenomicsGenomic analysis of axon pruning in Drosophila mushroom body neurons
Genomic analysis of axon pruning in Drosophila mushroom body neurons
PRJNA108199 | ENA
GenomicsPD1-mediated microglia assisted cerebrovascular pruning during vascular development.
PD1-mediated microglia assisted cerebrovascular pruning during vascular development.
PRJNA1157222 | ENA
TranscriptomicsMicroarray analysis of the self-pruning related transcriptome in sweet orange (Citrus sinensis) spring shoots
Transcriptome changes were also examined at three stages of SAM self-pruning utilizing microarray. Combining results from different stages, 1,573 differentially expressed genes were identified; the extensive repertoire of genes associated with programmed cell death, cell wall biosynthesis and metabo...
ORGANISM(S): Citrus sinensis 
2016-01-05 | E-GEOD-53579 | biostudies-arrayexpress
GenomicsTranscription-associated histone pruning demarcates macroH2A chromatin domains
Transcription-associated histone pruning demarcates macroH2A chromatin domains
PRJNA431857 | ENA
ProteomicsMicroglial SHIP1 controls synaptic pruning in the developing hippocampus via the complement system
INPP5D, which encodes the lipid phosphatase SHIP1, is one of the most common genes associated with the risk of Alzheimer’s disease and is enriched in microglia in the central nervous system. SHIP1 has been found to be highly expressed in plaque-associated microglia. However, how it regulates microgl...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-04 | PXD052118 | Pride
Complement Ship1 Synaptic pruning Inpp5d Microglia 
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