Sort   by:  
 Page size 

Despite intensive research and constant medical progress, sepsis remains one of the most urgent unmet medical needs of today. Most studies have been focused on the inflammatory component of the disease, however, recent advances support the notion that sepsis is accompanied by extensive metabolic ...

2020-01-10 | MTBLS1386 | MetaboLights

Cariogenic microorganisms as well as salivary metabolic status in early childhood caries (ECC) have been reported to differ from that in adult caries. The main aim of this study was to identify specific microbial species and salivary metabolites in children with ECC using species-specific qPCR an...

2024-11-12 | MTBLS10890 | MetaboLights
Many human infections are polymicrobial in origin, and interactions among community inhabitants shape colonization patterns and pathogenic potential1. However, few interspecies interactions have been functionally dissected at the molecular level or characterized on a systems level. Periodontitis, ...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 
2017-09-26 | PXD006153 | Pride
When Proteus mirabilis, Enterococcus faecalis, and Escherichia coli are co-cultured in human urine, they form biofilms with increased biomass. This increase in biomass is due to a rise in the total protein content of the biofilm rather than other components, such as carbohydrates or nucleic acids. T...
ORGANISM(S): Escherichia coli Proteus mirabilis HI4320 Bacteria Enterococcus faecalis (Streptococcus faecalis) 
2026-08-24 | PXD074670 | Pride
Chronic antibiotic-resistant polymicrobial infections are the leading cause of death in adults with cystic fibrosis (CF). We developed a polymicrobial culture model containing four genera that represents a ‘pulmotype’ detected in ~34% of lung infections in people with CF (pwCF), and accounts for 27%...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD076596 | Pride
The objectives of this investigation were to examine changes in the host transcriptional profiles during a polymicrobial periodontal pathogens Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia infection using a murine calvarial model of inflammation and bone resorption. P. gin...
ORGANISM(S): Mus musculus 
Catheter-associated urinary tract infections (CAUTI) account for 40% of all nosocomial infections and can lead to significant life-threatening complications such as bacteremia. Microbial biofilms play an important role in the development and pathogenesis of CAUTI, and these biofilms are often polymi...
ORGANISM(S): Proteus mirabilis HI4320 Enterococcus faecalis (Streptococcus faecalis) 
2025-05-06 | PXD041693 | Pride
To describe the transcriptional changes associated with polymicrobial-sepsis induced myocardial depression in wild type and iNOS deficient mice. Keywords: myocardium, contractility, differential gene expression, nitric oxide synthase, infection We compared the transcriptional profile of C57/BL6 WT m...
ORGANISM(S): Mus musculus 
Pseudomonas aeruginosa lasR is a keystone gene in polymicrobial cultures
Sort   by:  
 Page size