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TranscriptomicsDownregulation of LATS kinases alters p53 to promote cell migration
p53 is a pivotal tumor suppressor and a major barrier against cancer. We now report that silencing of the Hippo pathway tumor suppressors LATS1 and LATS2 in non-transformed mammary epithelial cells reduces p53 phosphorylation and increases its association with the p52 NF-?B subunit. Moreover, it par...
ORGANISM(S): Homo sapiens 
2015-12-11 | E-GEOD-74493 | biostudies-arrayexpress
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
ProteomicsYeast Mitochondrial Derived Vesicles (MDVs) have membrane potential and contain a functional ATP synthase
Mitochondria are responsible for the production of energy and for essential metabolic pathways in the cell, as well as fundamental processes such as apoptosis and aging. Interestingly, while the import machinery of proteins into mitochondria is thoroughly understood, there is currently no known prot...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-01-29 | PXD035192 | Pride
Mitochondrial derived vesicles Atp synthase 
ProteomicsYeast Mitochondrial Derived Vesicles (MDVs) have membrane potential and contain a functional ATP synthase-Part 2
Mitochondria are responsible for the production of energy and for essential metabolic pathways in the cell, as well as fundamental processes such as apoptosis and aging. Interestingly, while the import machinery of proteins into mitochondria is thoroughly understood, there is currently no known prot...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-01-29 | PXD039191 | Pride
Vesicles Atp synthase Yeast mitochondria 
ProteomicsMalaria Parasites Hijack Immune Host Splicing Machinery Using Decoy RNAs
Malaria, the most serious mosquito-borne parasitic disease, is mainly caused by the lethal parasite Plasmodium falciparum (Pf), which grows within human red blood cells (RBCs). This master of survival is known for utilizing sophisticated defense strategies to alter the host's immune response. Here, ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-17 | PXD054139 | Pride
Plasmodium falciparum Virulence Decoy rnas 
Proteomics20S proteasomes exported by malaria parasite promote its growth
Mature Red Blood Cells (RBCs) lack internal organelles and canonical defense mechanisms, making them both a fascinating host cell, in general, and an intriguing choice for the deadly malaria parasite Plasmodium falciparum (Pf), in particular. While growing inside RBCs, Pf are known to secrete multip...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD018154 | Pride
Malaria Phosphorylation Proteasome 
UnknownMitochondrial-derived vesicles retain membrane potential and contain a functional ATP synthase.
Not available
S-EPMC10157309 | biostudies-literature
UnknownPediatric Hospitalizations After School Reopening During the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Alpha (B.1.1.7) Variant Spread: A Multicenter Cross-sectional Study in Israel.
Not available
S-EPMC8807310 | biostudies-literature
UnknownNuclear import of malaria RNA rewires splicing in host immune cells
Not available
S-EPMC12932926 | biostudies-literature
ProteomicsBacillus subtilis spo0A trade-off
This project is about the proteomes of wild type cells (WT) and spo0A-null strain of B. subtilis during exponential growth in mannose medium. B2 & B4 corresponds to the wild type cells (two biological replicate samples) and B6 & B8 corresponds to spo0A-null data (two biological replicate samples).
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2023-05-10 | PXD039192 | Pride
Spo0a-null strain  b. subtilis  mannose medium 
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