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MetabolomicsImpact of microcin J25 on the porcine microbiome in a continuous culture model
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ORGANISM(S): swine colonic microbiota 
ST002014 | MetabolomicsWorkbench
MetabolomicsComprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation
In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...
2025-08-27 | MTBLS12325 | MetaboLights
MetabolomicsIdentification of Biomarkers using Metabolomics in Porcine Hemorrhagic Shock
Hemorrhagic shock with injury results in alterations of the metabolic state of an organism, which contribute to organ dysfunction and death. Previous investigations have explored the effects of carbohydrate prefeed in murine models but few in clinically relevant large animal models. We performed car...
2015-01-31 | MTBLS123 | MetaboLights
TranscriptomicsLIF-Dependent, Pluripotent Stem Cells Established from Inner Cell Mass of Porcine Embryos
The pig is important for agriculture and as an animal model in human and veterinary medicine, yet, despite over 20 years of effort, it has proved a difficult species from which to generate pluripotent stem cells analogous to those derived from mouse embryos. Here we report the production of LIF-depe...
ORGANISM(S): Sus scrofa 
2011-12-02 | E-GEOD-26369 | biostudies-arrayexpress
MetabolomicsLongitudinal Deep Multi-Omics Profiling in aCLN3Δex7/8Minipig Model Reveals Novel Biomarker Signatures for Batten Disease
Development of therapies for CLN3 Batten disease, a rare pediatric lysosomal storage disorder, has been hindered by the lack of etiological insights and translatable biomarkers to clinics. Here, we used a deep multi-omics approach to discover new biomarkers using longitudinal serum samples from a po...
2025-08-13 | MTBLS1107 | MetaboLights
TranscriptomicsTranscription profiling of pig alveolar macrophages infected with Porcine Respiratory Reproductive Syndrome Virus
A primary culture of Porcine Alveolar Macrophages (PAM) from six animals was split in two: one was infected at a multiplicity of infection (MOI) of 10 with a 13th passage of PRRSV Lelystad virus. The other culture was maintained as control. The percentage of infected cells ranged between 60 and 70% ...
ORGANISM(S): Sus scrofa 
2008-07-01 | E-MEXP-1350 | biostudies-arrayexpress
TranscriptomicsGene expression and muscle fiber function in a porcine ICU model
Background: Skeletal muscle wasting and impaired muscle function in response to mechanical ventilation and immobilization in intensive care unit (ICU) patients are clinically challenging partly due to (i) the poorly understood intricate cellular and molecular networks; and (ii) the unavailability of...
ORGANISM(S): Sus scrofa 
2009-08-31 | E-GEOD-16348 | biostudies-arrayexpress
TranscriptomicsAnalysis of porcine adipose tissue transcriptome reveals differences in de novo fatty acid synthesis in pigs with divergent muscle fatty acid composition
In pigs, adipose tissue is one of the principal organs involved in the regulation of lipid metabolism. It is particulary involved in the overall fatty acid synthesis with consequences in other lipid-target organs such as muscles and the liver. With this in mind, we have used massive, parallel high-t...
ORGANISM(S): Sus scrofa 
2014-03-31 | E-GEOD-52012 | biostudies-arrayexpress
TranscriptomicsDeciphering the porcine intestinal microRNA transcriptome
Background While more than 700 microRNAs (miRNAs) are known in human, a comparably low number has been identified in swine. Because of the close phylogenetic distance to humans, pigs serve as a suitable model for studying e.g. intestinal development or disease. Recent studies indicate that miRNAs a...
ORGANISM(S): Sus scrofa 
2010-05-05 | E-GEOD-21628 | biostudies-arrayexpress
TranscriptomicsDeep Sequencing of the Porcine Endometrial Transcriptome on Day 14 of Pregnancy
In pigs, conceptus attachment to the uterine surface epithelium starts around day 14 of pregnancy preceded by a pronounced vascularization at the implantation zones, initiating the epitheliochorial placentation. To characterize the complex transcriptome changes in the endometrium in the course of in...
ORGANISM(S): Sus scrofa 
2013-03-07 | E-GEOD-43667 | biostudies-arrayexpress
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