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ProteomicsThe Cystatin D Interactome Associated to Systemic Mastocytosis
he aim of the project is to characterize qualitatively and quantitatively the interaction of cystatin D in other protein partner and the formation of a complex in whole saliva of patients affected by different forms of systemic mastocytosis (SM), with and without skin involvement. The different comp...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042567 | Pride
Mastocytosis  high-resolution mass spectrometry  immunoprecipitation assay  cystatin d 
ProteomicsSoybean Symbiosome Membrane Proteome
Symbiosome membranes (SM) and symbiosome space (SS) fractions were isolated from nitrogen fixing soybean root nodules and analyzed using non-gel proteomic techniques. Bicarbonate stripping and chloroform-methanol extraction of isolated SM were used to enrich for hydrophobic integral membrane protein...
ORGANISM(S): Glycine max 
2015-08-12 | PXD001132 | Pride
Soybean Symbiosome Legume Membrane 
TranscriptomicsGenetic Loci that Regulate Ectopic Calcification in Response to Knee Trauma in LG/J by SM/J Advanced Intercross Mice
Ectopic calcification in synovial tissues is devastating to diarthrodial joints. While some forms of synovial ectopic calcification have genetically simple basis, most cases manifest as complex traits with environmental and multigenic components. The location of causal loci or the physiological proc...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-64793 | biostudies-arrayexpress
ProteomicsDirect lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly
M is the most abundant structural membrane protein in coronaviruses and is essential for the formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, Mshort and Mlong, and regulated transition between states is hypothesized to coordinate viral assembly and budding. However, th...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2026-07-09 | PXD079401 | Pride
Hdxms Sars-cov-2 Lipid interaction 
UnknownLong-term effects of pneumococcal conjugate vaccine on nasopharyngeal carriage of S. pneumoniae, S. aureus, H. influenzae and M. catarrhalis.
Not available
S-EPMC3382588 | biostudies-literature
ProteomicsProteomic dynamic changes in HDL subfractions from mouse plasma
HDL proteome dynamics may determine HDL cardioprotective functions. We aimed to characterize proteome and lipid profiles in small, medium and large (S/M/L) HDL fractions and analyze their functions. We characterized mouse HDL fractions by their high phospholipid (PL) content and collected S/M/L-HDL...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD011185 | Pride
Plasam Mouse Esi-ms/ms Hdl subfractions Hdl 
MetabolomicsIntegrated transcriptome and metabolome dynamics with phenotypic traits reveal regulatory basis of male morphotype differentiation in giant freshwater prawn Macrobrachium rosenbergii

This integrated multi-omics resource delineates the molecular and phenotypic trajectories underlying male morphotype differentiation (Blue Claw [BC], Orange Claw [OC], Small Male [SM]) in macrobrachium rosenbergii during determinative developmental stages (100, 110, and 120 days pos...

2025-08-22 | MTBLS12876 | MetaboLights
TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data]
Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29705 | biostudies-arrayexpress
TranscriptomicsLate stages of T-cell maturation in the thymus involve NF-κB and tonic type I interferon signaling
Positive selection occurs in the thymic cortex, but critical maturation events occur later in the medulla. We defined the precise stage at which T cells acquire competence to proliferate and emigrate. Transcriptome analysis of late gene changes suggested roles for NF-κB and interferon signaling. M...
ORGANISM(S): Mus musculus 
2016-04-03 | E-GEOD-74078 | biostudies-arrayexpress
MetabolomicsMolecular evidence of shipping noise impact on the blue mussel, a key species for the sustainability of coastal marine environments

Anthropogenic oceanic noise due to shipping has increased up to 32-fold over the last five decades, putting marine organisms at risk. While the impact of noise on marine mammals is well documented, its effect on molluscs, which hold immense economic and ecological importance, remain largely unkno...

2025-04-11 | MTBLS5678 | MetaboLights
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