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MetabolomicsFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...
2024-01-12 | MTBLS850 | MetaboLights
ProteomicsQuantitative serum proteomic analysis for potential biomarkers in post-COVID-19 onset Postural Orthostatic Tachycardia Syndrome (PC-POTS) patients
Postural orthostatic tachycardia syndrome (POTS) is a chronic neurological disorder of the autonomic nervous system (ANS) that is characterized by an excessive increase in heart rate upon orthostatic challenge. The symptoms of POTS are often debilitating, and it primarily affects young females. Even...
ORGANISM(S): Homo sapiens (Human) 
2025-05-08 | PXD052725 | Pride
Post-acute sequelae of covid-19 Post-covid-19 syndrome Mass spectrometry Postural orthostatic tachycardia syndrome Long covid syndrome Tandem mass tag Serum proteomics Biomarker 
MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
TranscriptomicsMultiple Early Factors Anticipate Post-Acute COVID-19 Sequelae
Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk-factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2...
ORGANISM(S): Homo sapiens 
2022-02-01 | E-MTAB-10129 | biostudies-arrayexpress
ProteomicsOxonium ion scanning mass spectrometry for large-scale plasma glycoproteomics
Protein glycosylation, a complex and heterogeneous post-translational modification that is frequently dysregulated in disease, has been difficult to analyse at scale. Here we report a data-independent acquisition technique for the large-scale mass-spectrometric quantification of glycopeptides in pla...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-29 | MSV000089567 | MassIVE
ProteomicsLongitudinal multi-omics analysis of convalescent individuals with respiratory sequelae 6–36 months after COVID-19
This study presents a longitudinal multi-omics analysis of COVID-19 convalescents with respiratory sequelae, spanning 6–36 months post-infection. The integrating proteomic and metabolomic profiling uncovers persistent molecular alterations, impaired diffusing capacity for carbon monoxide, and propos...
ORGANISM(S): Homo Sapiens 
2025-02-23 | PXD061113 |
Genomicshuman fecal metagenome
Faecal microbiota transplantation for sleep disturbance in post-acute COVID-19 syndrome
PRJNA1056888 | ENA
TranscriptomicsPolymorphisms associated with post-COVID-19 hyperglycemia using the Axiom Human Genotyping SARS-CoV-2 Research Array
To investigate the association between polymorphisms in innate immune genes and post-COVID-19 hyperglycemia
ORGANISM(S): Homo sapiens 
2025-08-30 | E-MTAB-15470 | biostudies-arrayexpress
ProteomicsProteomics reveals that immunoglobulin abnormalities and immune dysregulation in patients with post–COVID-19 condition
Vitamin D (VD) has a coordinated immune function. Decreased VD levels are closely related to the occurrence of post-COVID-19 Conditions (PCC), but the specific mechanism is still unclear. Methods: We collected 50 PCC patient serum samples and divided them into three groups by different VD levels: VD...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD059686 |
UnknownPost-acute COVID-19 syndrome.
Not available
S-EPMC8893149 | biostudies-literature
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