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MetabolomicsMitochondrial Transplantation of Brown Adipocytes Interferes with the Metabolism of Tumor Stem Cells and Inhibits the Recurrence of Brain Glioma after Operation

Glioblastoma multiforme (GBM) is highly aggressive, with treatment resistance and recurrence driven by metabolically plastic glioma stem cells (GSCs). Inspired by brown adipose tissue (BAT) thermogenesis, researchers transplanted BAT-derived mitochondria (BA-Mito) into GSCs, reducing stemness mar...

2025-08-27 | MTBLS12901 | MetaboLights
ProteomicsQuantitative proteomics reveals that distant recurrence-associated protein R-Ras and Transgelin predict post-surgical survival of colorectal cancer Stage III patients
Surgical resection is the major clinical intervention for Stage III colorectal cancer (CRC) currently. However, as much as 30.8% of the patients who had ever taken curative resection came out of recurrence eventually. Therefore, to facilitate formulating effective treatment plans, there is an intens...
ORGANISM(S): Homo sapiens (Human) 
2016-06-20 | PXD002903 | Pride
Transgelin. Stage iii colorectal cancer Prognostic biomarker Post-surgical recurrence R-ras Quantitative proteomics 
TranscriptomicsMicroRNA Profile Predicts Recurrence of Hepatocellular Carcinoma in Milan Criteria Cases with Mild Liver Cirrhosis.
In this study, we utilized microRNA expression profiling to assess risk of HCC recurrence after liver resection. We examined microRNA expression profiling in paired tumor and non-tumor liver tissues of 73 HCC patients with mild cirrhosis (Child-Pugh A/B) who satisfy Milan Criteria. We constructed pr...
ORGANISM(S): Homo sapiens 
2011-02-08 | E-GEOD-21362 | biostudies-arrayexpress
GenomicsA Cryogel-Based Dendritic Cell Vaccine for Post-Surgical Breast Cancer Immunotherapy
A Cryogel-Based Dendritic Cell Vaccine for Post-Surgical Breast Cancer Immunotherapy
PRJNA1222443 | ENA
TranscriptomicsA Cryogel-Based Dendritic Cell Vaccine for Post-Surgical Breast Cancer Immunotherapy
Triple-negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options. While surgical resection removes the primary tumor, it often fails to prevent recurrence or metastasis, and despite the promise of immunotherapy, the response to immune checkpoint bloc...
ORGANISM(S): Mus musculus 
2025-02-17 | GSE289340 | GEO
UnknownPrimary adipocytes as targetable drug depot to prevent post-surgical cancer recurrence.
Not available
S-EPMC10945205 | biostudies-literature
TranscriptomicsRecurrence_miRNAs
Using microarray-based technology, we have performed a microRNA expression analysis in 75 primary breast tumors from patients that either remained disease-free at 5 years post-surgery (group A) or developed early (group B) or late (group C) recurrence after surgical removal of the tumor and we have ...
ORGANISM(S): Homo sapiens 
2013-10-16 | E-MTAB-1989 | biostudies-arrayexpress
UnknownPhotothermal hydrogel platform for prevention of post-surgical tumor recurrence and improving breast reconstruction.
Not available
S-EPMC8499550 | biostudies-literature
GenomicsA nanovaccine targeting cancer stem cells and bulk cancer cells reduces post-surgical tumor relapse [RIP-Seq]
A nanovaccine targeting cancer stem cells and bulk cancer cells reduces post-surgical tumor relapse [RIP-Seq]
PRJNA1245168 | ENA
GenomicsA nanovaccine targeting cancer stem cells and bulk cancer cells reduces post-surgical tumor relapse [meRIP-seq]
A nanovaccine targeting cancer stem cells and bulk cancer cells reduces post-surgical tumor relapse [meRIP-seq]
PRJNA1245173 | ENA
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