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MetabolomicsPostnatal hyperglycemia alters amino acid profile in retinas
Not available
ORGANISM(S): Mus musculus 
ST002497 | MetabolomicsWorkbench
ProteomicsCombined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice
Introduction: Retinopathy of prematurity (ROP) with early vessel loss (Phase I) followed by uncontrolled vessel growth (Phase II) causes visual impairment in premature infants. Although supplementation with n-3 docosahexaenoic acid (DHA) alone has mixed results to prevent ROP, combined supplementati...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD061307 | Pride
Retinopathy of prematurity Dha Retinal vasculature Postnatal hyperglycemia 
TranscriptomicsProx1 downregulation is a prerequisite for the maturation and expansion of postnatal murine beta cells
Alterations in the expression of key transcription factors can be harmful for pancreatic beta cell homeostasis and could lead to diabetes. This study uncovered that Prox1 overexpression obstructs beta cell maturation and results in severe hyperglycemia. The function of β-cells is key for glucose ho...
ORGANISM(S): Mus musculus 
2016-02-11 | E-GEOD-68133 | biostudies-arrayexpress
UnknownPostnatal nutritional intakes and hyperglycemia as determinants of blood pressure at 6.5 years of age in children born extremely preterm.
Not available
S-EPMC6760565 | biostudies-literature
UnknownIntrauterine Hyperglycemia Is Associated with an Impaired Postnatal Response to Oxidative Damage.
Not available
S-EPMC5962324 | biostudies-literature
GenomicsIntrauterine hyperglycemia exposure per se altered metabolic functions in F2 offspring via reprogramming F1 PGCs
Intrauterine hyperglycemia exposure per se altered metabolic functions in F2 offspring via reprogramming F1 PGCs
PRJNA423101 | ENA
UnknownPostnatal hyperglycemia alters amino acid profile in retinas (model of Phase I ROP).
Not available
S-EPMC10568433 | biostudies-literature
Methylation profilingIntrauterine hyperglycemia exposure per se altered metabolic functions in F2 offspring via reprogramming F1 PGCs
Intrauterine hyperglycemia has been linked to an elevated risk of diabetes in next and further generations. Existing reports about transmission effects of intrauterine hyperglycemia have included both intrauterine and postnatal metabolic exposure factors, the impact of intrauterine hyperglycemia per...
ORGANISM(S): Mus musculus 
2017-12-20 | GSE108319 | GEO
TranscriptomicsComorbidity-Specific Molecular Programs of Early Diastolic Dysfunction Identify Glucocorticoid Receptor Activation as a Causal Driver in Obesity
Early diastolic dysfunction precedes the development of HFpEF, but the molecular events that initiate this process remain poorly defined. HFpEF arises in the setting of systemic comorbidities such as obesity, hypertension, hyperglycemia, and sleep apnea, which often coexist and make it difficult to ...
ORGANISM(S): Mus musculus 
2026-07-03 | E-MTAB-16848 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells from diabetic children
Objective: We hypothesized that type 1 diabetes (T1D) is accompanied by changes in gene expression in peripheral blood mononuclear cells (PBMCs) due to dysregulation of adaptive and innate immunity, counterregulatory responses to immune dysregulation, insulin deficiency and hyperglycemia. Research D...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9006 | biostudies-arrayexpress
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