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GenomicsProfiling Genome-wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
We have engineered the chromatin-modifying apparatus and formulated a novel technology, termed Clickable Chromatin Enrichment with parallel DNA sequencing (CliEn-seq), to probe genome-wide chromatin modification within living cells. Examine (E)-hex-2-en-5-ynylation mediated by engineered G9a Y1154A ...
ORGANISM(S): Homo sapiens 
2013-03-04 | E-GEOD-42792 | biostudies-arrayexpress
UnknownProfiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells.
Not available
S-EPMC3582175 | biostudies-literature
ProteomicsPosttranslation modification of NF-kB inducing kinase
2 This project is to identify the potential neddylation sites in human NF-kB inducing kinase (A.k.a. Map3K14). NIK-HA or NIK-HA in combination with FLAG-NEDD8 were co-expressed in HEK293T cells. NIK-HA were pulled down via denaturing immunoprecipitation protocol, subject to SDS-PAGE, in-gel trypsin ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD038653 | Pride
Human Nik 
GenomicsProfiling Genome-wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
We have engineered the chromatin-modifying apparatus and formulated a novel technology, termed Clickable Chromatin Enrichment with parallel DNA sequencing (CliEn-seq), to probe genome-wide chromatin modification within living cells.
ORGANISM(S): Homo sapiens 
2013-03-04 | GSE42792 | GEO
GenomicsHomo sapiens
Profiling Genome-wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
PRJNA183346 | ENA
ProteomicsChemical Proteomics Reveals Regulation of Bile Salt Hydrolases via Oxidative Post-translational Modifications
Bile salt hydrolase is a cysteine hydrolase that catalyzes the deconjugation of amino acids from bile acid amidates. The catalytic residue, cysteine 2, must be in a thiolate form for hydrolysis to occur. Using a chemical probe, CA-Dim (file name suffix 'D'), we identified cysteine 2 reversibly forms...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-27 | PXD074532 | Pride
Bile salt hydrolase Microbiome Chemoproteomics 
UnknownOverexpression of Exportin-5 Overrides the Inhibitory Effect of miRNAs Regulation Control and Stabilize Proteins via Posttranslation Modifications in Prostate Cancer.
Not available
S-EPMC5587889 | biostudies-literature
UnknownYeast ORC sumoylation status fine-tunes origin licensing.
Not available
S-EPMC9480853 | biostudies-literature
UnknownIdentification of histone acetylation markers in human fetal brains and increased H4K5ac expression in neural tube defects.
Not available
S-EPMC6900389 | biostudies-literature
UnknownUSP10 Regulates ZEB1 Ubiquitination and Protein Stability to Inhibit ZEB1-Mediated Colorectal Cancer Metastasis.
Not available
S-EPMC10239320 | biostudies-literature
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