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ProteomicsA simplified sample preparation for hair and skin proteins towards the application of archaeological fur and leather
Traditional protocols for proteomics analysis usually start by extracting or solubilizing the proteins from their substrates. This step can be challenging for archaeological proteins, when they are heavily contaminated or decayed. The remains of animal fur/leather objects from the singer’s burial of...
ORGANISM(S): Bos taurus (Bovine) Ovis aries 
2023-01-17 | PXD036745 | Pride
Collagen Archaeological burial Keratin Proteomics 
MetabolomicsWheat growth, applied water use efficiency and flag leaf metabolome under continuous and pulsed deficit irrigation

The intensity and frequency of precipitation events are predicted to change over the coming decades. For many areas, longer periods without rainfall are expected. We investigated the importance of irrigation frequency under water deficit conditions for growth, physiology and chemistry of wheat (<...

2020-09-23 | MTBLS1821 | MetaboLights
MetabolomicsHighly Species-Specific Foliar Metabolomes of Diverse Woody Species and Relationships with the Leaf Economics Spectrum
Plants show an extraordinary diversity in chemical composition and are characterized by different functional traits. However, relationships between the foliar primary and specialized metabolism in terms of metabolite numbers and composition as well as links with the leaf economics spectrum have rare...
2021-05-24 | MTBLS2414 | MetaboLights
ProteomicsLoss of RanBP9 cooperates with p53 deficiency to promote sarcomagenesis
Introduction: Ubiquitination is a major regulatory process that is often dysregulated in carcinogenesis. The C-terminal to LisH (CTLH) complex is a multi-subunit E3 ubiquitin ligase that has been shown to exert tumor-promoting and tumor-suppressing functions. Its core scaffolding subunit, RanBP9, h...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-21 | PXD081521 | Pride
Lc-msms E3 ligase Mef Mus musculus Global Ctlh complex 
ProteomicsSystem-wide profiling of protein-RNA interactions in sindbis infected cells reveals host regulators of infection
RNA viruses rely on cellular RNA-binding proteins (RBPs) to infect the host cell. However, the repertoire of the cellular RBPs exploited by viruses is largely unknown. Using the ‘RNA interactome capture’ method, we profiled in a proteome-wide scale the RBP-RNA interactions occurring during sindbis v...
ORGANISM(S): Homo sapiens (Human) Sindbis virus 
2019-02-28 | PXD009789 | Pride
Human Lc-msms Sindbis virus 
MetabolomicsGut-derived metabolites drive Th17 cell pathogenicity in multiple sclerosis

The gut-brain axis is an emerging factor in promoting multiple sclerosis (MS). However, the underlying mechanisms and strategies to target this axis are not established. Here, we investigated how the gut environment influences myelin-specific Th17 cell pathogenicity. We used the adoptive Th17 cel...

2025-08-15 | MTBLS980 | MetaboLights
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