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MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
UnknownPower doppler ultrasound signal predicts abnormal HDL function in patients with rheumatoid arthritis.
Not available
S-EPMC10125943 | biostudies-literature
ProteomicsBifidobacterium longum subsp. infantis utilizes urea as a nitrogen source
Bifidobacterium longum subsp. infantis is a bacterial commensal that colonizes the breast-fed infant gut where it utilizes indigestible components delivered in human milk. Accordingly, human milk contains several non-protein nitrogenous molecules, including urea at high abundance. This project inves...
ORGANISM(S): Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) 
2023-03-22 | PXD019401 | Pride
Bifidobacteria  microbiota  human milk  microbiome  urea 
GenomicsInternational Multiple Sclerosis Genomics Consortium (IMSGC) Genome Wide Association Study of Multiple Sclerosis

The goal of this study is to perform a comprehensive allelic and genotypic association analysis of the entire human genome in multiple sclerosis. The recent definitive linkage genome screen demonstrated that there is no other MS risk gene with an effect size anywhere near that of the MHC. How...

phs000139.v1.p1 | EGA
ProteomicsIdentification of DIR1-dependant cellular responses required for systemic acquired resistance in guard cells
After localized invasion by bacterial pathogens, systemic acquired resistance (SAR) is induced in uninfected plant tissues, resulting in enhanced defense against a broad range of pathogens. Although SAR requires mobilization of signaling molecules via the plant vasculature, the specific mechanisms r...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-17 | PXD024991 | Pride
Proteomics Arabidopsis thaliana Guard cells Lipidomics Metabolomics 
MetabolomicsExometabolomic-enabled discovery of compounds associated with Escherichia coli O157:H7 population dynamics in the lettuce phyllosphere

Contamination of fresh produce with human pathogens remains a serious public health and economic concerns due to the absence of effective kill steps in the farm-to-fork chain. In particular, the pathogenic Escherichia coli O157:H7 has been implicated in multiple illness outbreaks linked to lettuc...

2026-06-11 | MTBLS14653 | MetaboLights
ProteomicsBifidobacterium infantis metabolizes 2´fucosyllactose-derived and free fucose through a common catabolic pathway resulting in 1,2-propanediol secretion
Human milk oligosaccharides (HMOs) are highly diverse complex carbohydrates secreted in human milk. HMOs are indigestible by the infant and instead are metabolized by bifidobacteria in the infant gut microbiome to produce molecules that promote infant health and development. 2´fucosyllactose (2´FL) ...
ORGANISM(S): Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) 
2021-03-17 | PXD021868 | Pride
Human milk oligosaccharides Bifidobacteria Microbiome Fucose Microbiota 2'fucosyllactose 
ProteomicsAPIR: a universal FDR-control framework for boosting peptide identification power by aggregating multiple proteomics database search algorithms
Advances in mass spectrometry (MS) have enabled high-throughput analysis of proteomes in biological systems. The state-of-the-art MS data analysis relies on database search algorithms to quantify proteins by identifying peptide-spectrum matches (PSMs), which convert mass spectra to peptide sequences...
ORGANISM(S): Pyrococcus furiosus 
2021-09-21 | PXD028558 | Pride
Pyrococcus furiosus (pfu) Proteomics Complex proteomic standard 
UnknownLGBQ-affirmative cognitive-behavioral therapy for young gay and bisexual men's mental and sexual health: A three-arm randomized controlled trial.
Not available
S-EPMC9446477 | biostudies-literature
UnknownA Bioinformatics-Assisted Review on Iron Metabolism and Immune System to Identify Potential Biomarkers of Exercise Stress-Induced Immunosuppression.
Not available
S-EPMC8945881 | biostudies-literature
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