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In higher eukaryotes, PP2A phosphatase activity is embedded within two fundamentally different complex types. Canonical PP2A complexes are usually a trimeric assembly of scaffold, catalytic and regulatory subunits. Noncanonical PP2A, instead, is a dimeric component of the Integrator complex and, as ...
ORGANISM(S): Homo sapiens 
2026-10-05 | GSE306090 | GEO
In higher eukaryotes, PP2A phosphatase activity is embedded within two fundamentally different complex types. Canonical PP2A complexes are usually a trimeric assembly of scaffold, catalytic and regulatory subunits. Noncanonical PP2A, instead, is a dimeric component of the Integrator complex and, as ...
ORGANISM(S): Homo sapiens 
2026-10-05 | GSE306185 | GEO
In higher eukaryotes, PP2A phosphatase activity is embedded within two fundamentally different complex types. Canonical PP2A complexes are usually a trimeric assembly of scaffold, catalytic and regulatory subunits. Noncanonical PP2A, instead, is a dimeric component of the Integrator complex and, as ...
ORGANISM(S): Homo sapiens 
2026-10-05 | GSE306081 | GEO
Targeted protein degradation (TPD) has emerged as a highly promising therapeutic strategy for a wide range of diseases, including cancer and neurodegenerative disorders. The ubiquitin-proteasome system, which is responsible for protein degradation, plays a critical role in this process. Gaining comp...
ORGANISM(S): Homo sapiens (Human) 
2026-06-09 | PXD060403 | Pride
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