Sort   by:  
 Page size 
ProteomicsPP6 interated proteins in HaCaT cells treated with L-menthol
Because HES1 maintained PP6 protein level without affecting its mRNA level, we asked if HES1 directly interacted with PP6 in keratinocytes.
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD037336 | Pride
Igbp1 Pp6 Hacat L-menthol 
Proteomicspp6 is recruited in TNFalpha induced complex I
We identify pp6 is recruited in complex I induced by TNFalpha.
ORGANISM(S): Mus Musculus 
2021-12-14 | PXD030377 |
GenomicsArabidopsis PP6 phosphatases dephosphorylate PIF proteins to repress photomorphogenesis.
Arabidopsis PP6 phosphatases dephosphorylate PIF proteins to repress photomorphogenesis.
PRJNA527851 | ENA
GenomicsExploring synthetic lethality between the PP6 phosphatase and SETDB1
Exploring synthetic lethality between the PP6 phosphatase and SETDB1
PRJNA892551 | ENA
TranscriptomicsArabidopsis PP6 phosphatases dephosphorylate PIF proteins to repress photomorphogenesis.
Light-induced phosphorylation is necessary and essential for the degradation of phytochrome-interacting factors (PIFs), the central repressors of photomorphogenesis. Although the kinases responsible for PIF phosphorylation have been extensively studied, the phosphatases underlying PIF dephosphorylat...
ORGANISM(S): Arabidopsis thaliana 
2019-09-04 | GSE128498 | GEO
ProteomicsQuantitative Phosphoproteomics reveals new roles for PP6 in chromosome condensation and segregation
Protein phosphorylation by protein kinases and phosphatases is an important regulatory mechanism that controls mitotic progression. Protein Phosphatase 6 (PP6) is an essential enzyme with conserved roles in chromosome segregation and spindle assembly from yeast to humans. Here, we develop a baculovi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-07-27 | MSV000079201 | MassIVE
TranscriptomicsExploring synthetic lethality between the PP6 phosphatase and SETDB1
Genome wide CRISPR/Cas9 screening identified SETDB1 and the HUSH complex as a synthetic lethal interactor of the PP6 phosphatase. Here, we sought to discover the molecular basis for this synthetic lethality. SETDB1 is a histone H3 lysine 9 methyltransferase, reported to be important in the establish...
ORGANISM(S): Homo sapiens 
2025-10-20 | GSE216199 | GEO
UnknownThe protein phosphatase PP6 promotes RIPK1-dependent PANoptosis.
Not available
S-EPMC11134900 | biostudies-literature
UnknownArabidopsis PP6 phosphatases dephosphorylate PIF proteins to repress photomorphogenesis.
Not available
S-EPMC6778224 | biostudies-literature
TranscriptomicsAdaptation of HepG2 Cells to a Steady-State Reduction in the Content of Protein Phosphatase 6 (PP6) Catalytic Subunit
To assess the potential of PP6 as a therapeutic target in liver disorders, we attenuated expression of the PP6 catalytic subunit in HepG2 cells using lentiviral-transduced shRNA. Two PP6 knock-down (PP6KD) cell lines 18.5 and 19.5, (90% reduction of PP6-C protein content) were studied in depth. Both...
ORGANISM(S): Homo sapiens 
2015-06-01 | GSE67891 | GEO
Sort   by:  
 Page size