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To elucidate the PP6-upregulation mechanism of L-menthol, we took advantage of an unbiased target identification approach, DARTS, to identify the target of L-menthol in keratinocytes.
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD037335 | Pride
Because HES1 maintained PP6 protein level without affecting its mRNA level, we asked if HES1 directly interacted with PP6 in keratinocytes.
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD037336 | Pride
Interventions: 1.6% L-menthol Water with dimeticon Primary outcome(s): Neoplasma detection rate (number of detected neoplasms per patient) Study Design: Parallel Randomized
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