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ProteomicsPP2A Phosphatase Regulatory Subunit PPP2R3C is a New Positive Regulator of the Hedgehog Signaling Pathway
Cellular signaling pathways rely on posttranslational modifications (PTMs) to finely regulate protein functions, particularly transcription factors. The Hedgehog (Hh) signaling cascade, crucial for embryonic development and tissue homeostasis, is susceptible to aberrations that lead to developmental...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-10 | PXD054802 | Pride
Ppp2r3c  pp2a  phosphatases  hedgehog signaling  gli  phosphorylation  
ProteomicsPPP2R3C-GFP AP-MS from human RPE1 cells
Identification of proteins associated with human PPP2R3C, a regulatory subunit of the PP2A phosphatase
ORGANISM(S): Homo sapiens (Human) 
2024-09-25 | PXD054418 | Pride
Ppp2r3c Ap-ms 
UnknownA disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function.
Not available
S-EPMC11014585 | biostudies-literature
UnknownA disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function.
Not available
S-EPMC11496028 | biostudies-literature
UnknownCase Report: Novel Compound Heterozygotic Variants in PPP2R3C Gene Causing Syndromic 46, XY Gonadal Dysgenesis and Literature Review.
Not available
S-EPMC9259967 | biostudies-literature
UnknownFine-mapping and association analysis of candidate genes for papilla number in sea cucumber, Apostichopus japonicus.
Not available
S-EPMC10077181 | biostudies-literature
UnknownTranscriptome-wide association study identifies susceptibility genes for rheumatoid arthritis.
Not available
S-EPMC7821659 | biostudies-literature
UnknownImmunochip Meta-Analysis of Inflammatory Bowel Disease Identifies Three Novel Loci and Four Novel Associations in Previously Reported Loci.
Not available
S-EPMC6279085 | biostudies-literature
UnknownIntegrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.
Not available
S-EPMC11326171 | biostudies-literature
TranscriptomicsEffect of Okadaic Acid on gene expression in human pancreatic cells
Pancreatic ductal adenocarcinoma (PDAC) has a bad prognosis, a fast progression and is difficult to treat, highlighting the need for new therapeutic targets. Aggressive tumors mostly show Epithelial-to-Mesenchymal Transition (EMT). Protein phosphatase type 2A (PP2A) plays a central role in processes...
ORGANISM(S): Homo sapiens 
2023-05-16 | GSE216036 | GEO
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