Sort   by:  
 Page size 
TranscriptomicsPrecursor B cell development
Through differentiation-stage dependent analysis and pair wise comparisons between children and adults of 5 precursor B cell subsets, we identified several mechanisms that suggest tighter checkpoint control in adult precursor B cells.
ORGANISM(S): Homo sapiens 
2013-07-01 | E-MTAB-1422 | biostudies-arrayexpress
ProteomicsImproving Precursor Selectivity in Data Independent Acquisition Using Overlapping Windows
A major goal of proteomics research is the accurate and sensitive identification and quantification of a broad range of proteins within a sample. Data Independent Acquisition (DIA) approaches that acquire MS/MS spectra independently of precursor information have been developed to overcome the reprod...
ORGANISM(S): Bos Taurus Saccharomyces Cerevisiae 
2019-02-02 | PXD011910 | panorama
ProteomicsInvestigation of Oligodendrocyte Precursor Cell Differentiation by Quantitative Proteomics
Oligodendrocytes, the myelinating cells of the central nervous system, are essential for correct brain function. They originate from oligodendrocyte precursor cells (OPCs) through a differentiation process which is only incompletely understood and impaired in a variety of demyelinating diseases. Bet...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-06-21 | PXD012544 | Pride
Quantification Tmt labeling Oligodendrocytes Mass spectrometry Oligodendrocyte precursor cells 
TranscriptomicsThe basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor
Innate lymphoid cells (ILCs) are recently identified lymphocytes that limit infection and promote tissue repair at mucosal surfaces. However, the pathways underlying ILC development remain unclear. Here we show that the transcription factor NFIL3 directs the development of a committed bone marrow pr...
ORGANISM(S): Mus musculus 
2014-10-16 | E-GEOD-62337 | biostudies-arrayexpress
TranscriptomicsEbf2 is a selective marker of brown and beige adipogenic precursor cells (Microarray)
Brown adipocytes, muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown. Here, we prospectively isolated and determined the molecular profile of embryonic brown preadipose cells. Brown adipogenic p...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-60442 | biostudies-arrayexpress
TranscriptomicsEbf2 is a selective marker of brown and beige adipogenic precursor cells (RNA-seq)
Brown adipocytes, muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown. Here, we prospectively isolated and determined the molecular profile of embryonic brown preadipose cells. Brown adipogenic p...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-60441 | biostudies-arrayexpress
TranscriptomicsPARN mediates 3'-end trimming of Argonaute-cleaved precursor microRNAs
microRNAs (miRNAs) are typically generated as ~22-nucleotide double-stranded RNAs via processing of precursor hairpins by the RNase III enzyme Dicer, after which they are loaded into Argonaute (Ago) proteins to form RNA-induced silencing complex (RISC). However, the biogenesis of miR-451, an erythro...
ORGANISM(S): Danio rerio 
2013-11-13 | E-GEOD-51036 | biostudies-arrayexpress
TranscriptomicsMolecular analysis of precursor lesions in familial pancreatic cancer
Background: With less than a 5% survival rate pancreatic adenocarcinoma (PDAC) is almost uniformly lethal. In order to make a significant impact on survival of patients with this malignancy, it is necessary to diagnose the disease early, when curative surgery is still possible. Detailed knowledge of...
ORGANISM(S): Homo sapiens 
2013-03-27 | E-GEOD-43288 | biostudies-arrayexpress
TranscriptomicsHCMV infection of human neural precursor cells: Human neural precursor cell expression
HCMV -treated and control human adult neural precurso cells (NPC) were used to extract RNA for profiling on DNA arrays Primary adult hippocampus-derived neural precursor cells were used at passage # 2-4 for HCMV infection, followed by RNA extraction at indicated times Primary adult neural precursor ...
ORGANISM(S): Homo sapiens 
2012-07-21 | E-GEOD-30912 | biostudies-arrayexpress
ProteomicsDIA data analysis with unambiguously determined precursor mass
Proteomics research today no longer simply seeks exhaustive protein identification; now, robust, large-scale quantitative information is sought. For this purpose, data-independent acquisition (DIA) has emerged as a promising strategy largely owing to the developments in advanced mass spectrometers a...
ORGANISM(S): Homo sapiens (Human) 
2019-08-19 | PXD012744 | Pride
Precursor mass Dia 
Sort   by:  
 Page size