Preimplantation embryo development

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Transcriptomics (883)
Unknown (601)
Genomics (410)
Proteomics (91)
Methylation profiling (23)
Other (10)
Metabolomics (9)
Multiomics (2)
Models (1)
Genomic (1)

Organisms

Mus musculus (556)
Homo sapiens (246)
Bos taurus (68)
Danio rerio (49)
Drosophila melanogaster (34)
Sus scrofa (24)
Arabidopsis thaliana (16)
Caenorhabditis elegans (12)
Xenopus laevis (11)
Gallus gallus (9)
Rattus norvegicus (7)
Oryctolagus cuniculus (5)
Macaca mulatta (4)
Callithrix jacchus (3)
Canis lupus familiaris (3)
Strongylocentrotus purpuratus (3)
Sminthopsis crassicaudata (2)
Aplysia californica (2)
Sycon ciliatum (2)
Coturnix japonica (2)
Nematostella vectensis (2)
Anas platyrhynchos (2)
Hypsibius dujardini (1)
Schmidtea polychroa (1)
Mnemiopsis leidyi (1)
Oreochromis niloticus (1)
Amphimedon queenslandica (1)
Litomosoides sigmodontis (1)
Salvelinus fontinalis (1)
Meleagris gallopavo (1)

Organisms

Mus musculus (127)
Homo sapiens (52)
Bos taurus (31)
Sus scrofa (6)
Mus musculus musculus (2)
Capra hircus (2)
Macaca mulatta (2)
Bos indicus (1)
Oryctolagus cuniculus (1)
Ovis aries (1)

Repository

biostudies-arrayexpress (841)
ENA (260)
geo (192)
MassIVE (36)
EGA (30)
pride (21)
jPOST (16)
iProX (12)
MetaboLights (9)
PAXDB (4)
PanoramaPublic (3)
GPMDB (2)
Cell Collective (1)
dbGaP (1)

Tissue

Embryo (12)
Oocyte (8)
Embryonic stem cell (4)
Cell culture (2)
Blastocyst (1)
Embryonic stem cell line (1)
Sperm (1)
Egg (1)
Early embryonic cell (1)
Seminal plasma (1)
Stem cell (1)

Disease

Normal (9)
Not Available (2)
DNA damage (1)
Obesity (1)
Melanoma (1)
N/a (1)

Technology Type

Mass Spectrometry (21)
Shotgun proteomics (15)
Mass spectrometry (5)
Bottom-up proteomics (3)
Mass spectrometry assay (2)
Gel-based experiment (2)
Data-dependent acquisition (2)
Affinity purification coupled with mass spectrometry proteomics (2)
Illumina HiSeq 4000, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
NMR spectroscopy assay (1)
NMR spectroscopy (1)
SWATH MS (1)
Data-independent acquisition (1)

Instrument Platform

Illumina HiSeq 2500 (21)
Illumina HiSeq 4000 (21)
Illumina HiSeq 2000 (19)
Illumina NovaSeq 6000 (17)
NextSeq 500 (15)
Illumina Genome Analyzer II (5)
NextSeq 2000 (5)
Illumina NovaSeq X (4)
Illumina Genome Analyzer IIx (3)
NextSeq 550 (3)
HiSeq X Ten (2)
Illumina MiSeq (2)
STAR v2.5.3a, rpkmforgenes, RSeQC 2.6.1 (1)
Illumina Nextera XT index kits (Set A–D) (1)
Oligo(dT) primer and SuperScript II reverse transcriptase (ThermoFisher Scientific), TapeStation 4200 or 2100 Bioanalyzer with a DNA High Sensitivity chip (Agilent Biotechnologies) (1)
Aria III (BD Biosciences) (1)
Standard computational workstation (1)
Agilent 2100 Bioanalyzer (Agilent Technologies); Qubit Fluorometer (Thermo Fisher Scientific); standard electrophoresis system (1)
NanoDrop spectrophotometer, Agilent 2100 Bioanalyzer (1)
G2565BA Microarray Scanner (1)
Genepix (1)
Covaris S220 (1)
AB SOLiD 4 System (1)
G2500A GeneArray scanner [Agilent Technologies] (1)
ScanArray 5000 [PerkinElmer] (1)
418 [Affymetrix] (1)
G2565BA DNA microarray scanner [Agilent] (1)
Affymetrix Fluidics Station 400 (1)
None (1)
Illumina HiSeq 1000 (1)

Publication Date

2014 (113)
2010 (111)
2012 (101)
2013 (91)
2015 (80)
2011 (71)
2016 (66)
2024 (56)
2025 (55)
2008 (52)
2023 (48)
2009 (45)
2026 (39)
2022 (34)
2020 (28)
2021 (26)
2019 (24)
2007 (24)
2017 (22)
2018 (18)
2004 (12)
2006 (7)
2005 (3)

UNIPROT ID/AC

Q6DD11_XENLA (3)
A0A1L8FM65_XENLA (3)
Q8AVM8_XENLA (3)
A0A1L8GUG3_XENLA (3)
Q7ZYR1_XENLA (3)
A0A1L8I323_XENLA (3)
Q5BIX5_XENLA (3)
Q6INK7_XENLA (3)
A2RRW9_XENLA (3)
A0A1L8HFA1_XENLA (3)
A0A1L8FTL8_XENLA (3)
Q6WSQ3_XENLA (3)
A0A1L8FNA6_XENLA (3)
A0A1L8GWN2_XENLA (3)
Q6GLM7_XENLA (3)
A0A1L8GTK1_XENLA (3)
Q6GNV0_XENLA (3)
A0A1L8HFU6_XENLA (3)
Q7ZY58_XENLA (3)
A3KND1_XENLA (3)
A0A1L8GMS5_XENLA (3)
Q7ZXL1_XENLA (3)
Q5PQ24_XENLA (3)
Q7ZY57_XENLA (3)
A0A1L8GR83_XENLA (3)
A0A1L8FVB8_XENLA (3)
A0A1L8H632_XENLA (3)
A0A1L8ERT1_XENLA (3)
A0A1L8EQ61_XENLA (3)
Q804V4_XENLA (3)

CHEBI ID

CHEBI:30769 (5)
CHEBI:32816 (5)
CHEBI:30794 (4)
CHEBI:18012 (4)
CHEBI:15741 (4)
CHEBI:30915 (4)
CHEBI:26271 (4)
CHEBI:25017 (4)
CHEBI:42111 (3)
CHEBI:17306 (3)
CHEBI:17992 (3)
CHEBI:32365 (3)
CHEBI:48131 (3)
CHEBI:30746 (3)
CHEBI:16196 (3)
CHEBI:26984 (3)
CHEBI:17351 (3)
CHEBI:15891 (3)
CHEBI:15940 (3)
CHEBI:15354 (3)
CHEBI:1148 (3)
CHEBI:16856 (3)
CHEBI:15428 (3)
CHEBI:16449 (3)
CHEBI:16958 (3)
CHEBI:17822 (3)
CHEBI:6650 (3)
CHEBI:16737 (3)
CHEBI:22660 (3)
CHEBI:18237 (3)

Metabolite Name

Pyruvic acid (4)
Succinic acid (4)
Citric acid (4)
Malonic acid (4)
Lactic acid (3)
Valine (3)
Leucine (3)
Adenosine monophosphate (3)
Nicotinic acid (3)
Benzoic acid (3)
Fumaric acid (3)
Lysine (3)
Asparagine (3)
Serine (3)
Alanine (3)
2-Hydroxybutyric acid (3)
Proline (3)
Phenylalanine (3)
Maltose (3)
Isoleucine (3)
Azelaic acid (3)
Glutamic acid (3)
Glycine (3)
Creatinine (3)
Taurine (3)
Sucrose (3)
Threitol (2)
Ribonic acid (2)
Arabitol (2)
Arabinose (2)

First Public Date

2024 (37)
2025 (32)
2014 (31)
2026 (28)
2023 (23)
2022 (23)
2019 (20)
2021 (18)
2020 (15)
2018 (12)
2017 (9)
2016 (6)
2015 (5)
2013 (1)

Study type

Transcription profiling by array (474)
RNA-seq of coding RNA (125)
ChIP-seq (69)
Methylation profiling by high throughput sequencing (25)
RNA-seq of coding RNA from single cells (21)
Methylation profiling by array (20)
ChIP-chip by array (17)
RNA-seq of non coding RNA (17)
ChIP-chip by tiling array (8)
Comparative genomic hybridization by array (8)
Other (8)
Transcription profiling by SAGE (6)
Unknown experiment type (6)
Animal - High-throughput sequencing (4)
Bisulfite-seq (3)
ATAC-seq (3)
Single nucleus RNA sequencing (3)
CUT&RUN (3)
RNA-seq of total RNA (3)
Animal - Single-cell sequencing (2)
RNAi profiling by array (2)
RIP-seq (2)
Cell line - Single-cell sequencing (1)
Differential (1)
Cell line - One-color microarray (1)
Cell line - High-throughput sequencing (1)
Trajectory (1)
Genotyping by array (1)
Transcription profiling by RT-PCR (1)
MicroRNA profiling by high throughput sequencing (1)

Release Date

2014 (116)
2010 (112)
2015 (110)
2012 (110)
2016 (99)
2013 (99)
2011 (79)
2025 (76)
2020 (74)
2023 (68)
2021 (63)
2022 (62)
2024 (58)
2008 (57)
2009 (52)
2017 (48)
2019 (45)
2018 (35)
2007 (33)
2026 (15)
2006 (10)
2005 (10)
2004 (10)
2001 (1)

Lab affiliation

Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (3)
Instituto Superior de InvestigacionesBiológicas (INSIBIO), CONICET‐UNT, and Instituto de Biología “Dr. FranciscoD. Barbieri,” Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina (1)
Max Planck Institute for Molecular Bioemedicine, Bioanalytical Mass Spectroemtry (1)
Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. (1)
Max Planck Institut for Molecular Biomedicine Bioanalytical Mass Spectrometry Röntgenstr. 20 48159 Münster Germany (1)
Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University Schoole of Medicine (1)
Department of Molecular Mechanisms of Disease, DMMD University of Zurich 8057 Zurich Switzerland (1)
John van Geest Cancer Research Centre, Nottingham Trent University (1)
Huazhong University of Science and Technology 13 Hangkong Road, Wuhan, 430030 P.R. China (1)
Laboratory of RNA Biology International Institute of Molecular and Cell Biology in Warsaw (1)
Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine (1)
The Third Affiliated Hospital of Guangzhou Medical University, Peking University Third Hospital. (1)
State Key Laboratory of Reproductive Medicine and Offspring Health (1)
Radboud Universiteit Nijmegen (1)
Max Planck Institute for Molecular Biomedicine Bioanalytical Mass Spectrometry Röntgenstr. 20 48149 Münster Germany (1)
Yale University Department of Molecular Biophysics and Biochemistry (1)
ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, B-9000 Ghent, Belgium (1)
Center for Genomic Regulation (1)
Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China (1)

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Unique metabolic regulation of micromeres contributes to their inductive signaling in the sea urchin embryo

In many multicellular organisms, a group of cells called organizers plays critical roles by sending signals to adjacent cells and controlling patterning events such as embryogenesis and tissue morphogenesis. Recent studies suggest that these organizers or inductive cells facilitate the downstream...

2025-07-07 | MTBLS5017 | MetaboLights

Maternal lipid mobilization is essential for embryonic development in a key malaria vector

Lipid metabolism is an essential component in reproductive physiology. While lipid mobilization has been implicated in the growth of Plasmodium falciparum malaria parasites in their Anopheles vectors, the role of this process in the reproductive biology of these mosquitoes remains elusive. Here, we ...

2024-11-05 | MTBLS9881 | MetaboLights

Comparative proteomic landscapes provide insights into mammalian preimplantation development and failure

Understanding mammalian preimplantation development, particularly in humans, at the proteomic level remains limited. Here, we applied our comprehensive solution of ultrasensitive proteomic technology to measure the proteomic profiles of oocytes and early embryos and identified nearly 8,000 proteins ...

ORGANISM(S): Mus musculus (Mouse)

2025-02-05 | PXD054371 | Pride

Transcription profiling of preimplantation mouse embryo development

Preimplantation mouse embryo development study on Affymetrix MOE430A. Zeng et al (2004) Dev Biol 272:483-496.

ORGANISM(S): Mus musculus

2008-06-11 | E-GEOD-1744 | biostudies-arrayexpress

Comparative proteomic landscapes provide insights into mammalian preimplantation development

Proteins play a crucial role in the central dogma as the end product of gene expression. However, a deep proteomic landscape is still the missing puzzle piece of the comprehensive understanding of mammalian preimplantation development. Here, using our recently developed Comprehensive Solution of Ult...

ORGANISM(S): Mus musculus (Mouse)

2025-11-27 | PXD043363 | Pride

Protein turnover Mouse preimplantation development Multi-omics analysis Zygotic genome activation (zga) Ultrasensitive proteomics Cross species analysis

Transcription profiling of mouse embryo to assess gene expression during preimplantation mouse development

Studies using low-resolution methods to assess gene expression during preimplantation mouse development indicate that changes in gene expression either precede or occur concomitantly with the major morphological transitions, that is, conversion of the oocyte to totipotent 2-cell blastomeres, compact...

ORGANISM(S): Mus musculus

2007-10-23 | E-GEOD-1749 | biostudies-arrayexpress

Transcription profiling of mouse embryo development

Preimplantation mouse embryo development on Affymetrix MOE430B. Zeng et al (2004) Dev Biol 272:483-496.

ORGANISM(S): Mus musculus

2008-06-11 | E-GEOD-1745 | biostudies-arrayexpress

In vivo rabbit preimplantation development

Evaluation of the transcriptomic profile of the rabbit embryo along the preimplantation period during in vivo development. Three embryonic stages were used: four cell embryos (H32 post-coïtum); morula (H58 pc) and blastocyst (H90 pc). Keywords: time course rabbit embryo 18 samples

ORGANISM(S): Oryctolagus cuniculus

2008-11-30 | E-GEOD-12084 | biostudies-arrayexpress

The footprint of embryonic genome activation on the proteome of mouse preimplantation development

The transformation of a fertilized oocyte into a multicellular embryo comprised of differentiated cells depends on the processing of genetic orders, first in the form of transcripts and then of proteins. Our current understanding of mouse development has greatly benefited from the analysis of transc...

ORGANISM(S): Mus musculus (Mouse)

2019-10-23 | PXD007082 | Pride

Lc-msms Mouse development Silac Preimplantation Oocyte

Transcription profiling of mouse embryo development U74Av2

Preimplantation mouse embryo development study on Affymetrix U74Av2. Zeng et al Dev Biol (2004) 272:483-496.

ORGANISM(S): Mus musculus

2008-06-11 | E-GEOD-1391 | biostudies-arrayexpress

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