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TranscriptomicsSex-specific effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene x environment interactions
prenatal stress response, genetic modification Background: Prenatal stress (PS) exposure has been shown to increase the risk for emotional disorders in later life. Furthermore, the serotonin transporter (5-HTT) genotype is suggested to exert a modulating effect on the association between early life ...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-26025 | biostudies-arrayexpress
ProteomicsNeurodevelopmental Impact of Prenatal Stress: A Proteomic Analysis of Myelination Disruptions in the Avian Embryo
Prenatal stress induced by maternal activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequent release of glucocorticoids can profoundly affect fetal brain development. This study investigates the molecular mechanisms underlying prenatal stress in Gallus gallus domesticus by analyzin...
ORGANISM(S): Gallus gallus (Chicken) 
2025-10-27 | PXD055206 | Pride
Gallus gallus domesticus Proteomics Myelin Prenatal stress Corticosterone 
TranscriptomicsDNA methylation in CD34 positive cells derived from cord blood at birth following prenatal stress
DNA methylation profiling of CD34 positive cells derived from cord blood at birth following prenatal stress The groups consist of 8 individuals with low levels of prenatal stress (control) and 10 individuals with high levels of prenatal stress (stress)
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-84018 | biostudies-arrayexpress
TranscriptomicsDNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm
Background: Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and physical outcomes in the offspring. Although epigenetic processes may be responsible for PNMS effects, human research is hampered by the lack of experimental methods that parallel controlled animal studies. Disaste...
ORGANISM(S): Homo sapiens 
2015-08-26 | E-GEOD-72354 | biostudies-arrayexpress
TranscriptomicsPrenatal stress-induced programming of genome-wide promoter DNA methylation in 5-Htt deficient mice
The serotonin transporter (5-HTT) gene-linked polymorphic region has been suggested to play a modulatory role in mediating the effects of early-life stress on psychopathology rendering carriers of the low-expression short (s)-allele more vulnerable to environmental adversity in later life. Here we a...
ORGANISM(S): Mus musculus 
2014-11-18 | E-GEOD-51634 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Rattus norvegicus hippocampus cells under prenatal stress
The study determined whether there were gender differences in the
expression of hippocampal genes in adult rats in association with dissimilarity
in their behavior, and how these were affected by prenatal stress. Pregnant
Wistar rats were subjected to varied stress once daily on days 14-...
ORGANISM(S): Rattus norvegicus 
2010-01-01 | E-MEXP-2470 | biostudies-arrayexpress
GenomicsEpigenomic profiling in fetal brain after prenatal stress
Epigenomic profiling in fetal brain after prenatal stress
PRJNA843693 | ENA
GenomicsRNASeq analysis of offspring ileum tissue following Prenatal stress
RNASeq analysis of offspring ileum tissue following Prenatal stress
PRJNA637902 | ENA
ProteomicsPhosphoproteomic profiling of hippocampus from offspring rats exposed to prenatal stress
Prenatal stress (PS) could cause depression of offprsing. Here, relative quantitative phosphoproteomics of hippocampus of PS-S and CON offspring rats were performed using LC-MS/MS to confirm known pathways and identify new areas of depression. A total of 6,790 phosphopeptides, 9,817 phosphorylation ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-12-30 | PXD019117 | Pride
Hippocampus Rat Lc-ms/ms 
GenomicsPrenatal stress reprograms placental signaling and opposes maternal immune activation effects in the fetal brain
Prenatal stress reprograms placental signaling and opposes maternal immune activation effects in the fetal brain
PRJNA1530618 | ENA
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