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GenomicsEnhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest
Here we derive human and chimpanzee cranial neural crest cells (CNCCs) and profile histone modifications, transcription factors, chromatin accessibility and gene expression to systematically and quantitatively annotate evolutionary divergence of craniofacial cis-regulatory landscapes. Histone modifi...
ORGANISM(S): Homo sapiens 
2015-09-11 | E-GEOD-70751 | biostudies-arrayexpress
TranscriptomicsExpression profiles of primary bone marrow derived mouse macrophages M-bM-^@M-^S untreated and treated with LPS or LPS+PGE
The polarization of macrophages into an anti-inflammatory or regulatory phenotype plays an important role in resolving inflammation. PGE2 regulates macrophage polarization via a PKA dependent pathway. PKA phosphorylates SIKs, inhibiting their ability to phosphorylate CRTC3 in cells. This in turn ...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-41833 | biostudies-arrayexpress
UnknownAnti-Mullerian hormone concentration is associated with central adiposity and reproductive hormones in expectant fathers.
Not available
S-EPMC9790283 | biostudies-literature
UnknownData resource profile: the ORIGINS project databank: a collaborative data resource for investigating the developmental origins of health and disease.
Not available
S-EPMC11949255 | biostudies-literature
TranscriptomicsSarcoidosis-specific markers from whole blood gene expression
We hypothesized that microarray analyses of whole blood gene expression would identify patterns of gene expression useful in the diagnosis for sacroidosis and identify inflammatory mediators relevant to the underlying pathophysiology. We analyzed whole blood RNA from 37 patients with sarcoidosis, 20...
ORGANISM(S): Homo sapiens 
2011-08-10 | E-GEOD-19314 | biostudies-arrayexpress
UnknownHelios is a key transcriptional regulator of outer hair cell maturation.
Not available
S-EPMC6542691 | biostudies-literature
UnknownCross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia.
Not available
S-EPMC4146418 | biostudies-literature
UnknownEffect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial.
Not available
S-EPMC6439674 | biostudies-literature
UnknownAnalysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.
Not available
S-EPMC4806328 | biostudies-literature
UnknownPrenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study.
Not available
S-EPMC6386638 | biostudies-literature
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