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TranscriptomicsDeletion of Tardbp Down-Regulates Tbc1d1, a Gene Linked to Obesity, and Alters Body Fat Metabolism
Tat Activating Regulatory DNA Binding Protein (Tardbp or TDP-43), a highly conserved metazoan DNA/RNA binding protein thought to be involved in RNA transcription and splicing, has been linked to the pathophysiology of amyotrophic lateral sclerosis and frontotemporal lobar degeneration and is essenti...
ORGANISM(S): Mus musculus 
2010-07-15 | E-GEOD-21993 | biostudies-arrayexpress
TranscriptomicsRNA-seq of pancreatic CAF-derived cell line 0082T treated with Autotaxin inhibitors (IOA-289 and PF-8380) against DMSO treated controls
Autotaxin (ATX), encoded by ENPP2, catalyzes the production of lysophosphatidic acid (LPA), an important regulator within the tumor microenvironment (TME). ATX is a clinical target in pancreatic ductal adenocarcinoma (PDAC), yet the pro-tumorigenic action of the ATX/LPA axis in PDAC remains unclear....
ORGANISM(S): Homo sapiens 
2024-10-06 | E-MTAB-14494 | biostudies-arrayexpress
MetabolomicsSeasonal and day/night variations of microbial metabolic functioning in simulated cloud water

Microorganisms maintain metabolic activity in clouds, with recognized impacts on chemical reactivity by contributing to the processing of small organic compounds, radicals and their precursors. However, the conditions in clouds can be highly contrasted (temperature, light, etc), and it remains un...

2026-02-12 | MTBLS12281 | MetaboLights
UnknownMercury in Neotropical birds: a synthesis and prospectus on 13 years of exposure data.
Not available
S-EPMC10622370 | biostudies-literature
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Klebsiella pneumoniae complex
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Klebsiella variicola Homo sapiens (Human) Klebsiella pneumoniae 
2021-07-05 | PXD016672 | Pride
Proteomics Rpmi Swath Klebsiella pneumoniae Sera Antibiotic resistance Sepsis 
ProteomicsProteomic characterization of MEIOC interactants: part 2
Identification of MEIOC interactants by immunoprecipitation and shotgun proteomics
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079991 | MassIVE
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. brucei assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-09-23 | MTBLS1474 | MetaboLights
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights
ProteomicsGut Microbial Ecosystem Multiomics in Inflammatory Bowel Disease
Using multiple omics approaches to explore the effect of the gut microbial ecosytem on inflammatory bowel disease
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2019-07-02 | MSV000084050 | MassIVE
UnknownPostoperative critical care and high-acuity care provision in the United Kingdom, Australia, and New Zealand.
Not available
S-EPMC6435907 | biostudies-literature
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