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ProteomicsIn-depth proteomics and natural peptidomics analyses of human endometrial fluid
Endometrial fluid reflects the status of the endometrium, being a good atraumatic source of information on embryo implantation and some pathological conditions. Although some attempts have been made to characterize it, the catalogue of the human endometrial fluid proteins remains incomplete and litt...
ORGANISM(S): Homo sapiens (Human) 
2020-09-29 | PXD016707 | Pride
Natural peptidomics Timstof Endometrial fluid 
ProteomicsDetermining changes in the oxidized proteome of human CD8+ T cells with enhancing proteasome activity
Chronic T cell receptor (TCR) stimulation, combined with adverse conditions in the tumor microenvironment (TME) such as hypoxia and nutrient deprivation, frequently results in T cell exhaustion. Exhausted T cells (TEX) experience oxidative stress, which causes an accumulation of oxidized proteins wi...
ORGANISM(S): Homo sapiens (Human) 
2026-03-12 | PXD070152 | Pride
Exhausted t cells (tex) Oxidative stress Proteasome 
ProteomicsBinding of the spike of SARS-CoV-2 to steatotic hepatocytes promotes metabolic dysfunction
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a multi-organ damage that includes hepatic dysfunction, which has been observed in over 50% of COVID-19 patients. Liver injury in COVID-19 patients could be attributed to the cytopathic effects induced by the interation between the ...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD035263 | Pride
Sars-cov-2  hace2 mice  liver energy metabolism  nash  metformin 
ProteomicsMS-based analysisi of the role of protein neddylation in the context of T-cell-mediated anti-tumor immunity (1)
Neddylation is one type of post-translational modification (PTM) by which the ubiquitin-like molecule NEDD8 is covalently attached to protein substrates, in a process that depends on NAE1 (NEDD8 activating enzyme E1 regulatory subunit). Here we study the role of protein neddylation in the context of...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-15 | PXD050527 | Pride
Mass spectrometry Nae1 Nedd8 Mln4924 
ProteomicsMS-based analysis of the role of protein neddylation in the context of T-cell-mediated anti-tumor immunity (2)
Neddylation is one type of post-translational modification (PTM) by which the ubiquitin-like molecule NEDD8 is covalently attached to protein substrates, in a process that depends on NAE1 (NEDD8 activating enzyme E1 regulatory subunit). Here we study the role of protein neddylation in the context of...
ORGANISM(S): Homo sapiens (Human) 
2025-04-15 | PXD050529 | Pride
Mass spectrometry Nae1 Nedd8 Mln4924 
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. CCD18 Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083961 | MassIVE
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. Ramos Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083967 | MassIVE
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. Jurkat Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083966 | MassIVE
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. MCF7 Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083962 | MassIVE
ProteomicsChr16-HPP. Shotgun Analysis improvement. JPR HPP Special issue 2013. MCF7 Cell line.
The Chromosome 16 Consortium is integrated in the Human Proteome Project that aims to develop an entire map of the proteins encoded by the human genome following a gene-centric strategy (C-HPP) to make progress in the understanding of human biology in health and disease (B/D-HPP). To do this study f...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083960 | MassIVE
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