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Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells. By incorporating an mRNA for a reporter protein into these microvesicles, we demonstrate th...
ORGANISM(S): Homo sapiens 
Microvascular inflammation and endothelial injury, triggered by interferon-gamma (IFNgamma), are hallmarks of antibody-mediated rejection (ABMR), the leading cause of premature kidney allograft loss. Chronic ABMR exhibits glomerular basement membrane and extracellular matrix (ECM) remodeling and end...
ORGANISM(S): Homo sapiens (Human) 
2026-10-15 | PXD074919 | Pride
Microvascular inflammation and endothelial injury, triggered by interferon-gamma (IFNgamma), are hallmarks of antibody-mediated rejection (ABMR), the leading cause of premature kidney allograft loss. Chronic ABMR exhibits glomerular basement membrane and extracellular matrix (ECM) remodeling and end...
ORGANISM(S): Homo sapiens (Human) 
2026-10-15 | PXD074969 | Pride
Cell-to-cell interactions between tumor cells and their microenvironment are critical determinants of tumor tissue biology and therapeutic responses. Interactions between glioblastoma (GBM) cells and endothelial cells (ECs) establish a purported stem cell niche. We hypothesized that genes that media...
ORGANISM(S): Homo sapiens 
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