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TranscriptomicsElectric stimulation of neonatal rat ventricular cardiomyocytes
Study on changes in gene expression in primary cultures of neonatal rat ventricular cardiomyocytes to electric stimulation. Through comparing non-stimulated, stimulated and blebbistatin supplemented and stimulated cultures we set out to identify the genes that are specifically activated by electric ...
ORGANISM(S): Rattus norvegicus 
2009-12-10 | E-GEOD-15856 | biostudies-arrayexpress
TranscriptomicsComparison of neonatal and adult rat ventricular cardiomyocytes
We addressed the question of which protein kinases are expressed in cardiomyocytes. We assessed the changes during postnatal development, comparing profiles in rat neonatal ventricular cardiomyocytes (NVMs) with adult ventricular cardiomyocytes (AVMs). Neonatal and adult rat ventricular cardiomyocyt...
ORGANISM(S): Rattus norvegicus 
2015-01-01 | E-MTAB-2832 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neonatal rat ventricular cardiac myocytes treated with interleukin 33 for 0.5, 1 or 2 hours
Study of the effect of interleukin 33 (IL33) on transcript expression in neonatal rat ventricular cardiac myocytes at 0.5, 1 or 2 h
ORGANISM(S): Rattus norvegicus 
2010-04-01 | E-MEXP-1912 | biostudies-arrayexpress
TranscriptomicsExpression data from pooled biological replicates (n=6) from MEF2D knockdown in neonatal rat ventricular myocytes (NRVMs)
Differentiation and maintenance of cardiac muscle is a complex biological process. MEF2D appears to play an important role in the regulation of cardiomyocyte homeostasis. We knocked down expression of MEF2D in NRVMs, and assessed global expression pattern changes in MEF2D knockdown against a negativ...
ORGANISM(S): Rattus norvegicus 
2015-08-31 | E-GEOD-72157 | biostudies-arrayexpress
TranscriptomicsHuman Mesenchymal Stem Cells in Cardiomyocyte Co-Culture
Evaluate the change in transcription factors that have a role in human mesenchymal stem cell (hMSC) commitment to a cardiomyocyte lineage when co-cultured for 4 days with rat neonatal cardiomyocytes and before acquiring a recognizable cardiac phenotype. A myocardial microenvironment was generated b...
ORGANISM(S): Homo sapiens 
2011-09-15 | E-GEOD-32171 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cultured rat cardiomyocytes grown with eicosapentaenoic acid or docosahexaenoic acid supplementation in the culture media
Despite the recognized protective effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in cardiovascular diseases, and the demonstration of the control of gene expression by polyunsaturated fatty acids (PUFAs), the effects of these n-3 fatty acids on the whole genoma has never been ...
ORGANISM(S): Rattus norvegicus 
2008-05-07 | E-GEOD-4327 | biostudies-arrayexpress
TranscriptomicsEffect of Nocturnal Hemodialysis (NHD) on Cardiomyocyte Gene Expression
Frequent hemodialysis is associated with improvement in myocardial mechanics and cardiac gene expression profile Uremic plasma (10%) before and after NHD was added to cultures of Neonatal Sprague-Dawley rat ventricular myocytes
ORGANISM(S): Rattus norvegicus 
2012-08-02 | E-GEOD-28723 | biostudies-arrayexpress
TranscriptomicsTranscript expression levels of neonatal mouse cardiomyocytes mock-transfected, or transfected with cel-miR-67, hsa-miR-590-3p or hsa-miR-199a-3p
To identify the relevant targets of the selected miRNAs, we assessed global transcriptome changes by deep-sequencing total neonatal mouse cardiomyocyte RNA after transfection with hsa-miR-590-3p or hsa-miR-199a-3p Four condition experiment; one replicate per condition; mouse neonatal cardiomyocytes ...
ORGANISM(S): Mus musculus 
2012-10-13 | E-GEOD-41538 | biostudies-arrayexpress
TranscriptomicsmiR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.
miR-222 overexpression leads to promotion of proliferation and hypertrophy and inhibition of apoptosis in in primary neonatal rat ventricular cardiomyocytes (NRVMs). Isolated primary neonatal rat ventricular cardiomyocytes were plated in 6 cm BD Primaria tissue culture dishes. Transfection of microR...
ORGANISM(S): Rattus norvegicus 
2016-03-03 | E-GEOD-59641 | biostudies-arrayexpress
ProteomicsNeonatal rat cardiomyocyte RBPome
Mutations or decreased expression of RNA-binding proteins (mRBPs) can lead to cardiomyopathies in humans. Here we defined RBPs in healthy and diseased primary cardiomyocytes at a system-wide level by RNA Interactome Capture. This identified 67 novel cardiomyocyte specific RBPs including several cont...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-07-08 | PXD019811 | Pride
Heart Lc-ms Cardiomyocyte Rna-binding protein 
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