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TranscriptomicsTranscription profiling of S. cerevisiae novel response to microtubule perturbation in meiosis
Cells were grown to saturation in YPD (YEP + 2% glucose) for 24 hours, diluted into YPA (YEP + 2% potassium acetate) at OD600= 0.3 and grown over night at 30C. Cells were washed with sterilized water the next day and re-suspended in SPII medium (0.3% potassium acetate, pH = 7.0) at OD600= 1.9 to ind...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-11 | E-GEOD-1693 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mammalian male germ cells undergoing mitotic growth, meiosis and gametogenesis in highly enriched cell populations
We report a comprehensive large-scale expression profiling analysis of mammalian male germ cells undergoing mitotic growth, meiosis and gametogenesis using High Density Oligonucleotide Microarrays and highly enriched cell populations. Among 11955 rat loci investigated, 1268 were identified as differ...
ORGANISM(S): Rattus norvegicus 
2004-03-01 | E-MEXP-31 | biostudies-arrayexpress
ProteomicsThe EXOSC10S402T allele identified in colon cancer causes early embryonic lethality and suggests EXOSC10 as a biomarker for 5-fluorouracil sensitivity
The conserved 3’-5’ exoribonuclease EXOSC10/Rrp6 degrades and processes aberrant mRNAs and non-coding RNAs in cooperation with the RNA exosome. The protein is phosphorylated and ubiquitinated and it’s subcellular localization and stability are controlled during stress responses via sumoylation and t...
ORGANISM(S): Homo sapiens (Human) 
2026-03-20 | PXD061578 | Pride
Rrp6 5-fluorouracil Exosc10 Ubiquitination 
TranscriptomicsTranscription profiling of yeast over-expressing the meiosis-specific gene SPO13 during the mitotic cell cycle
Effect of overexpression of the meiosis-specific gene SPO13 during mitotic cell cycle
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-31 | E-MEXP-1459 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae (budding yeast) ume6 deletion strains vs wild-type in different media to determine the complement of Ume6 dependent genes during mitosis and meiosis
To determine the complement of Ume6-dependent genes expressed during mitosis and/or meiosis in budding yeast we compared wild-type and
ume6 deletion strains using Yeast 2.0 high density oligonucleotide microarrays (GeneChips). Samples were analysed from cells growing in rich medium with fermentab...
ORGANISM(S): Saccharomyces cerevisiae 
2014-10-01 | E-TABM-192 | biostudies-arrayexpress
TranscriptomicsHigh-Resolution Profiling of Novel Transcribed Regions During Rat Spermatogenesis
Mammalian spermatogenesis is a complex and highly orchestrated combination of processes in which male germline proliferation and differentiation result in the production of mature spermatozoa. If recent genome-wide studies have contributed to the in-depth analysis of the male germline protein-coding...
ORGANISM(S): Rattus norvegicus 
2014-06-01 | E-GEOD-48321 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of testicular biopsies with Sertoli-cell-only and spermatogonial presence
The aim of the study was to identify in vivo spermatogonial gene expression within the context of their biological niche. Identification of spermatogonial genes was done by t-testing on the replicates of Score 3 (Spermatogonia) and Score 2 (SCO) testicular biopsies. 3 biological replicates with sper...
ORGANISM(S): Homo sapiens 
2009-11-12 | E-GEOD-18997 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation to determine binding of ARS binding factor 1 (Abf1) in yeast during vegetative growth and meiotic development
Binding of the yeast ARS binding factor 1 (Abf1) to target promotors during vegetative growth and meiotic development as tested by ChIP-CHIP analysis;
ORGANISM(S): Saccharomyces cerevisiae 
2008-05-01 | E-MEXP-1439 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle from amyotrophic lateral sclerosis sod1(G86R) axotomized mice and control mice to monitor denervation-dependent gene expression in an Amyotrophic lateral sclerosis (ALS) mouse model
Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neuromuscular disorder characterized by the selective degeneration of upper and lower motor neurons, progressive muscle wasting and paralysis. To define the full set of alterations in gene expression in skeletal muscle during the course of t...
ORGANISM(S): Mus musculus 
2008-01-05 | E-TABM-195 | biostudies-arrayexpress
TranscriptomicsEGR4 is a master gene responsible for fertility in cryptorchidism
RNA was isolated from testicular biopsies of cryptorchid boys. Gene expression profiles for these samples were investigated using Affymetrix arrays Whole testicular tissue was gained from cryptorchid boys aged 10 Months to 4.5 years as well as from controls of identical age. Each biopsy sample was c...
ORGANISM(S): Homo sapiens 
2009-09-01 | E-GEOD-16191 | biostudies-arrayexpress
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