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MetabolomicsGSDME-controlled pyroptosis promotes muscle repair by coordinating tissue resident macrophages and fibro-adipogenic progenitors
GSDME (Gasdermin E) is a critical protein known for its role in pyroptosis, a form of programmed cell death associated with inflammation. We demonstrated that GSDME as a crucial mediator in muscle repair, particularly in the context of muscle damage induced by cardiotoxin (CTX). Specifically, we fou...
2026-01-05 | MTBLS10509 | MetaboLights
MetabolomicsMetabolomics analysis of stress erythroid progenitors
Not available
ORGANISM(S): Mus musculus 
ST002009 | MetabolomicsWorkbench
MetabolomicsIsotope tracing analysis of stress erythroid progenitors
Not available
ORGANISM(S): Mus musculus 
ST002007 | MetabolomicsWorkbench
MetabolomicsMetabolomics analysis of stress erythroid progenitors (Part 2)
Not available
ORGANISM(S): Mus musculus 
ST002499 | MetabolomicsWorkbench
MetabolomicsMetabolomic Profiling of Human Pluripotent Stem Cell Differentiation into Lung Progenitors
Not available
ORGANISM(S): Homo sapiens 
ST002055 | MetabolomicsWorkbench
TranscriptomicsExpression data from Tcf1 deficient and Tcf1 wildtype cultured bone marrow lymphoid primed progenitors after four days on Notch ligand expressing stroma (OP9-DL4).
Tcf1 is necessary for optimal T lineage development. Tcf1 deficient progenitors fail to initiate the T lineage program in vitro and development is severely defective in vivo. We used microarrays to assess the overal global gene expression differences from Tcf1 wildtype and deficient lymphoid biased ...
ORGANISM(S): Mus musculus 
2011-08-03 | E-GEOD-26559 | biostudies-arrayexpress
ProteomicsMass spectrometry analysis of mouse hematopoietic stem cells and their progenitors reveals differential expression within and between proteome and transcriptome throughout adult and aged hematopoiesis
mass spectrometry analysis of aged and adult hematopoietic stem cells, multipotent progenitors and oligopotent progenitors
ORGANISM(S): Mus musculus (Mouse) 
2021-07-24 | PXD017442 | Pride
Hematopoiesis Early blood progenitors Stem cells Hematopoietic stem cells Aging 
TranscriptomicsMicroarray evaluation of in vitro cultured Sox9+ mouse lung progenitors isolated from E12.5 embryonic lung progenitors
The study aims to show that Sox9+ Chd1+ mouse embryonic lung progenitors can be isolated and expanded long-term in 3D culture while maintaining their multipotency. in vitro cultured Sox9+ Chd1+ lung progenitors transcriptionally resemble their in vivo counterparts and show significant difference fr...
ORGANISM(S): Mus musculus 
2017-11-01 | E-MTAB-6086 | biostudies-arrayexpress
ProteomicsEml1-associated proteins in mouse neural progenitors
Echinoderm microtubule (MT)-associated protein-like 1 (Eml1) is mutated in the HeCo mouse, which exhibits subcortical band heterotopia (SBH), a developmental malformation of the cerebral cortex. EML1 mutations are also found in human patients affected by severe ribbon-like heterotopia, associated wi...
ORGANISM(S): Mus musculus (Mouse) 
2017-12-19 | PXD006837 | Pride
Neural progenitors Mouse Microtubules Eml1 Cortical development 
TranscriptomicsTranscriptome analysis of self-renewing human pancreatic progenitors derived from pluripotent stem cells
Human pluripotent stem cells were differentiated into PDX1+/NKX6-1+ Pancreatic Progenitors (PPd15 cells), which were subsequently captured and expanded in culture. These culture Pancreatic Progenitors (cPP cells) were capable of self-renewal and could be passaged up to 20 times. Furthermore, cPP cel...
ORGANISM(S): Homo sapiens 
2017-06-06 | E-MTAB-5731 | biostudies-arrayexpress
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