Sort   by:  
 Page size 
ProteomicsDifferential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases
The hydroxylation of proline residues to 4-trans-hydroxyproline (Hyp) is a common post-translational protein modification in plants, mediated by prolyl 4-hydroxylases (P4Hs). Hyps predominantly occur in a group of cell wall proteins, the Hydroxyproline-rich glycoproteins (HRGPs), where they are freq...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2024-08-10 | PXD051497 | Pride
O-glycosylation Posttranslational protein modification Erythropoietin Prolyl-hydroxylation Biopharmaceutical Plant-made pharmaceutical 
ProteomicsProline hydroxylation of collagens in prolyl 4-hydroxylase mutant mice
Collagen from the skin of wild type and prolyl 4-hydroxylase mutant mice was extracted and proline hydroxylation of the collagen-derived peptides were analyzed by LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2018-04-10 | PXD008802 | Pride
Mouse Collagen prolyl 4-hydroxylase 
UnknownDifferential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases.
Not available
S-EPMC11252719 | biostudies-literature
TranscriptomicsTuning the transcriptional response to hypoxia through HIF prolyl- and asparaginyl-hydroxylase inhibition:Sequencing Data
The hypoxia inducible factor (HIF) system orchestrates cellular responses to hypoxia in animals. HIF is an /-heterodimeric transcription factor that regulates the expression of hundreds of genes in a context dependent manner. A hypoxia-sensing component of the HIF system involves oxygen-dependent ca...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-MTAB-4264 | biostudies-arrayexpress
UnknownProlyl 4-hydroxylation regulates Argonaute 2 stability.
Not available
S-EPMC2661850 | biostudies-literature
UnknownMolecular foundations of collagen triple helical assembly: the central role of prolyl-4-hydroxylation.
Not available
S-EPMC12862961 | biostudies-literature
ProteomicsProlyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer
Protein hydroxylation extensively regulates cellular signaling by affecting protein stability, protein-protein interaction and protein activity, and its dysregulation contributes to the pathogenesis of various diseases including cancers. However, because of the transient nature of the enzyme-substra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-02 | MSV000086231 | MassIVE
UnknownDecoding elegant interplay among different stereo-electronic effects due to the ancient prolyl-4-hydroxylation stabilizing collagenous helicity.
Not available
S-EPMC12059709 | biostudies-literature
UnknownProlyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin.
Not available
S-EPMC5865229 | biostudies-literature
ProteomicsAnalysis of prolyl 4-hydroxylation of P4ha1 KO MEFs and P4ha2 KO mouse kidneys
We established a mouse embryonic fibroblast (MEF) cell line derived from mice that have a genetic ablation of of P4ha1. Type I collagen produced by these cells in presence of ascorbate was collected and partially purified by precipitation. Site specific hydroxylation analysis was performed using mas...
ORGANISM(S): Mus musculus (Mouse) 
2023-12-15 | PXD035945 | Pride
Mouse Prolyl 4-hydroxylation Collagen 
Sort   by:  
 Page size