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Testing the effect of 80 small molecules on the interaction between 250 protein pairs
ORGANISM(S): Saccharomyces cerevisiae 
For the identification of HTRA2-specific protein interaction partners in retinal tissues of the house swine (Sus scrofa), we performed co-immunoprecipitation experiments with recombinant 6His-tag HTRA2 followed by quantitative LC-MS-based proteomics (see Fig. 2A and File S1). In brief, 2 µg recombin...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2021-10-11 | PXD024442 | Pride
Insulin resistance and Type 2 diabetes are marked by an aberrant response in the insulin signaling network. The phosphoinositide-dependent serine/threonine kinase, Akt2, plays a key role in insulin signaling and glucose uptake, most notably within skeletal muscle. Protein-protein interaction regul...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-30 | PXD002557 | Pride
MYC-MIZ1 protein interaction in germinal center.
Kaiso is a novel TAZ-interaction partner that promotes hepatic stellate cell activation and regulates the downstream lncRNA HIF1A-AS3
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