Sort   by:  
 Page size 
ProteomicsCovalent Protein Painting on Cancer Cell Lines
Cancer cells were labeled with Covalent Protein Painting and resulting peptides analyzed by mass spectrometry. For further information, please see: bioRxiv 2020.01.31.929117; doi: https://doi.org/10.1101/2020.01.31.929117
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-28 | MSV000085034 | MassIVE
ProteomicsCellular protein painting for structural and binding sites analysis via lysine reactivity profiling with o-phthalaldehyde
The three-dimensional structure and the molecular interaction of proteins determine their roles in many cellular processes. Chemical protein painting with protein mass spectrometry can identify changes in structural conformations and molecular interactions of proteins including their binding sites. ...
ORGANISM(S): Homo Sapiens 
PXD046150 |
ProteomicsCovalent Protein Painting in AD
The 3D structures of aberrant protein folds have been visualized in detail in vitro, yet no method has been able to quantitatively measure protein misfolding across a proteome in vivo. Covalent protein painting is a mass spectrometry-based structural proteomics approach to quantify the protein surfa...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-12 | MSV000083031 | MassIVE
ProteomicsPalaeoproteomics guidelines to identify proteinaceous binders in artworks following the study of a 15th‑century painting by Sandro Botticelli’s workshop
Undertaking the conservation of artworks informed by the results of molecular analyses has gained growing importance over the last decades, and today it can take advantage of state-of-the-art analytical techniques, such as mass spectrometry-based proteomics. Protein-based binders are among the most ...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) Gallus gallus (Chicken) Ovis aries Capra hircus (Goat) 
2022-07-05 | PXD024397 | Pride
Lc-msms Cultural heritage Mass spectrometry Paint binders Palaeoproteomics 
UnknownPalaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting.
Not available
S-EPMC6032867 | biostudies-literature
TranscriptomicsChromatin IP of POF, HP1 and H3K9ac in S2 cells and salivary glands.
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8296 | biostudies-arrayexpress
ProteomicsIntegrating Cell Painting and Thermal Proteome Profiling for Inference of Targets and Mechanism of Action
Understanding the mechanism of action (MoA) of bioactive compounds is a central challenge in drug discovery and chemical biology. In this article, we propose a strategy for integrating morphological data with proteomics to provide deeper insights into the MoA of compounds. We combine the rich phenot...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD065743 | Pride
Thermal proteome profiling Mechanism of action Drug target Cell painting 
UnknownProtein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.
Not available
S-EPMC4109009 | biostudies-literature
ProteomicsPalaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting
Ahead of display, a non-original layer was observed on the surface of a fragment of a wall painting by Ambrogio Lorenzetti (active 1319, died 1348/9). FTIR analysis suggested proteinaceous content. Mass spectrometry was used to better characterise this layer and revealed two protein components: shee...
ORGANISM(S): Bos taurus (Bovine) Anas platyrhynchos Gallus gallus (Chicken) Ovis aries 
2018-04-05 | PXD008486 | Pride
Cultural heritage Proteomics Mass spectrometry Conservation science Posttranslational modifications 
TranscriptomicsChromatin IP of POF, HP1 and H3K9ac and transcript profiling in S2 cells and salivary glands
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8301 | biostudies-arrayexpress
Sort   by:  
 Page size