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ProteomicsIntegrated with Proteome-sequencing, bulk RNA-sequencing and Single cell RNA-sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration
We selected humann intervertebral disc samples to perform proteomics analysis. There were 1 case of grade I , 1 case of grade II, 3 cases of grade Ⅲ and 3 cases of grade Ⅳ according to Pfirrmann classfication. RNA seqencing analysis and single-cell RNA sequencing were integrated with proteomics data...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD040593 | Pride
Intervertebral disc degeneration Proteome-sequencing 
GenomicsEfficient detection of alternative spliced human proteome using translatome sequencing
Efficient detection of alternative spliced human proteome using translatome sequencing
PRJNA816171 | ENA
ProteomicsExopeptidase assisted N- and C-terminal proteome sequencing
Due to mechanisms such as alternative translation starts or proteolytic processing, in-vivo proteoforms do not necessarily correspond to those encoded in the genome. Therefore, knowledge of protein termini is an indispensable prerequisite to understand protein function. Sequencing of protein N- and ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-10-15 | PXD015612 | Pride
Protein sequencing Proteomics Terminomics 
UnknownDecoding the chromatin proteome of a single genomic locus by DNA sequencing.
Not available
S-EPMC6059479 | biostudies-literature
UnknownWhole-genome sequencing analysis of the cardiometabolic proteome.
Not available
S-EPMC7729872 | biostudies-literature
ProteomicsLung proteome sequencing of Tibetan sheep
To reveal the protein expression patterns in Tibetan sheep lungs at different altitudes, proteome sequencing was performed in this study.
ORGANISM(S): Ovis Aries 
2021-12-30 | PXD030661 |
TranscriptomicsEfficient detection of alternative spliced human proteome using translatome sequencing
Alternative splicing (AS) isoforms create numerous proteoforms, expanding the complexity of the genome. Highly similar sequences, incomplete reference databases and the insufficient sequence coverage of mass spectrometry limit the identification of AS proteoforms.In this work, we compared RNC-seq an...
ORGANISM(S): Homo sapiens 
2022-06-22 | GSE198624 | GEO
UnknownProtocol for analysis of RNA-sequencing and proteome profiling data for subgroup identification and comparison.
Not available
S-EPMC9133752 | biostudies-literature
TranscriptomicsTranscription profiling by high throughput sequencing of HeLa human cancer cell line
Illumina single-end sequencing of Hela_2 (HeLa cell line). While the number and identity of proteins expressed in a single human cell type is currently unknown, this fundamental question can be addressed by advanced mass spectrometry (MS)-based proteomics. On-line liquid chromatography coupled to hi...
ORGANISM(S): Homo sapiens 
2011-11-12 | E-MTAB-823 | biostudies-arrayexpress
UnknownEfficient Detection of the Alternative Spliced Human Proteome Using Translatome Sequencing.
Not available
S-EPMC9201276 | biostudies-literature
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