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Virus sp. strain:provirus | isolate:host Genome sequencing
Haloferax volcanii harbours four putative proviruses: Halfvol1, Halfvol2, Halfvol3 and Halfvol4. In this study we successfully deleted all four provirus genomes, demonstrating, that they are not essential. Transcriptome comparison between this strain (∆Halfvol1-4) and a wild type strain reveals an i...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) 
2025-05-26 | PXD058393 | Pride
Our study reports the first genome-wide atlas of functional nodes that mediate proviral silencing in ESCs. It provides evidences for the comprehensive, interconnected and multi-layered genetic/epigenetic machineries by which ESCs maintain the repressive state of provirus and ERVs. ChIP-seq analysis...
ORGANISM(S): Mus musculus 
Our study reports the first genome-wide atlas of functional nodes that mediate proviral silencing in ESCs. It provides evidences for the comprehensive, interconnected and multi-layered genetic/epigenetic machineries by which ESCs maintain the repressive state of provirus and ERVs. RNA-seq analysis t...
ORGANISM(S): Mus musculus 
Chromatin maturation of the HIV provirus in primary resting CD4+ T cells
Transcriptome analysis of Haloferax volcanii provirus-free strain vs wild-type H100
Human immunodeficiency virus (HIV) infection is a chronic condition, where viral DNA integrates into the genome. The fate of the provirus determines the infection course. Latently infected cells form a persistent, heterogeneous reservoir. The reservoir that reinstates an active infection comprises c...
ORGANISM(S): Homo sapiens 
2019-12-16 | GSE121055 | GEO
We propose a technology B-HIVE, which allows us to map HIV integrations in a cell population and measure their individual transcription. The principle of B-HIVE is to tag individual viral genomes with a unique barcode of 20 nucleotides that allows us to track the viral transcripts produced by each p...
ORGANISM(S): Homo sapiens 
2016-09-17 | GSE82061 | GEO
The chromatin landscape at the HIV-1 provirus integration site determines viral expression
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