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ProteomicsPhosphoproteomics analysis identifies novel candidate substrates of the non-receptor tyrosine kinase, SRMS
SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) or PTK 70 (Protein tyrosine kinase 70) is a non-receptor tyrosine kinase that belongs to the BRK family kinases (BFKs). The gene encoding SRMS was first discovered in 1994. Yet to date less is known ...
ORGANISM(S): Homo sapiens (Human) 
2018-03-08 | PXD006809 | Pride
Frk Srms Substrates Brk Mass spectrometry Ptk6 Src Phosphoproteomics Ptk 70 
UnknownThe impact of UV cross-linking on corneal stromal cell migration, differentiation and patterning.
Not available
S-EPMC10825899 | biostudies-literature
UnknownStructure-based drug design and AutoDock study of potential protein tyrosine kinase inhibitors.
Not available
S-EPMC3044423 | biostudies-literature
UnknownTyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors.
Not available
S-EPMC1924855 | biostudies-literature
UnknownPhosphoproteomics Analysis Identifies Novel Candidate Substrates of the Nonreceptor Tyrosine Kinase, Src-related Kinase Lacking C-terminal Regulatory Tyrosine and N-terminal Myristoylation Sites (SRMS).
Not available
S-EPMC5930402 | biostudies-literature
UnknownModulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures.
Not available
S-EPMC2659629 | biostudies-literature
UnknownS gene mutations of HBV in children with HBV-associated glomerulonephritis.
Not available
S-EPMC3311139 | biostudies-literature
GenomicsFirst genome-wide association study in an Australian Aboriginal population provides insights into genetic risk factors for Body Mass Index and Type 2 Diabetes
A body mass index (BMI) >22kg/m2 is a risk factor for type 2 diabetes (T2D) in Aboriginal Australians. To identify loci associated with BMI and T2D we undertook a genome-wide association study using 1,355,133 quality-controlled single nucleotide polymorphisms (SNPs) genotyped (Illumina 2.5M Duo Bea...
EGAS00001001004 | EGA
TranscriptomicsModulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
This SuperSeries is composed of the following subset Series: GSE35701: CP001: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy GSE35703: CP003: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy Refer to individual Serie...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35705 | biostudies-arrayexpress
TranscriptomicsCP001: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35701 | biostudies-arrayexpress
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