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ProteomicsPhosphoproteomics analysis identifies novel candidate substrates of the non-receptor tyrosine kinase, SRMS
SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) or PTK 70 (Protein tyrosine kinase 70) is a non-receptor tyrosine kinase that belongs to the BRK family kinases (BFKs). The gene encoding SRMS was first discovered in 1994. Yet to date less is known ...
ORGANISM(S): Homo sapiens (Human) 
2018-03-08 | PXD006809 | Pride
Frk Srms Substrates Brk Mass spectrometry Ptk6 Src Phosphoproteomics Ptk 70 
ProteomicsGlobal phosphoproteomic analysis identifies SRMS-regulated signaling intermediates
The non-receptor tyrosine kinase, SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) is a member of the BRK family kinases (BFKs) which represents an evolutionarily conserved relative of the Src family kinases (SFKs). Tyrosine kinases are known to re...
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD009234 | Pride
Frk Srms Brk Mass spectrometry Ptk5 Ptk6 Ptk70 Src Phosphoproteomics Non-receptor tyrosine kinase 
GenomicsEffect of SRMS deficiency on gene expression upon cisplatin treatment in human ovarian cancer cells
Effect of SRMS deficiency on gene expression upon cisplatin treatment in human ovarian cancer cells
PRJNA849762 | ENA
TranscriptomicsEffect of SRMS deficiency on gene expression upon cisplatin treatment in human ovarian cancer cells
This study was designed to evaluate the transcriptomic alterations upon SRMS deficiency after cisplatin exposure in a human ovarian cancer cell line.
ORGANISM(S): Homo sapiens 
2023-06-07 | GSE206226 | GEO
UnknownGlobal phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates.
Not available
S-EPMC6098843 | biostudies-literature
UnknownStructure, Function, and Regulation of the SRMS Tyrosine Kinase.
Not available
S-EPMC7352994 | biostudies-literature
UnknownROS-mediated SRMS activation confers platinum resistance in ovarian cancer.
Not available
S-EPMC10231978 | biostudies-literature
UnknownSeeking a better understanding of the non-receptor tyrosine kinase, SRMS.
Not available
S-EPMC10220380 | biostudies-literature
UnknownThe nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.
Not available
S-EPMC8202955 | biostudies-literature
UnknownFrom urban dust and marine sediment to Ginkgo biloba and human serum-a top ten list of Standard Reference Materials (SRMs).
Not available
S-EPMC8748289 | biostudies-literature
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