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UnknownPolypharmacology-based kinome screen identifies new regulators of KSHV reactivation.
Not available
S-EPMC10503724 | biostudies-literature
UnknownPolypharmacology-based kinome screen identifies new regulators of KSHV reactivation.
Not available
S-EPMC9915688 | biostudies-literature
ProteomicsGlobal phosphoproteomic analysis identifies SRMS-regulated signaling intermediates
The non-receptor tyrosine kinase, SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) is a member of the BRK family kinases (BFKs) which represents an evolutionarily conserved relative of the Src family kinases (SFKs). Tyrosine kinases are known to re...
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD009234 | Pride
Frk Srms Brk Mass spectrometry Ptk5 Ptk6 Ptk70 Src Phosphoproteomics Non-receptor tyrosine kinase 
GenomicsIntegrative genomic profiling of hepatocellular adenomas reveals recurrent FRK activating mutations and mutational processes of malignant transformation
Hepatocellular adenomas (HCA) are benign liver tumors predominantly developed in women using oral contraception. Here, exome sequencing identified novel recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 activation and cell proliferation sensitive to Src inhibitors. We a...
EGAS00001000679 | EGA
ProteomicsLarge-scale Discovery of Substrates of the Human Kinome (FRK) [Reanalysis: JPST000508]
Kinase -networks are important for cellular signal transduction. Despite tremendous efforts to uncover these signaling pathways, huge numbers of uncharacterized phosphosites still remain in the human proteome. Because of the transient nature of kinase-substrate interactions in vivo, it is almost imp...
ORGANISM(S): Homo Sapiens (human) 
2024-02-21 | RPXD049754 | JPOST Repository
TranscriptomicsComparative study of gene expression in human primary astrocytes induced with 6 different neuroinvasive bacteria
Primary human astrocytes challenged with either 1. Borrelia, 2. Streptococcus, 3. Neisseria, 4. Listeria, 5. E.coli, 6. Klebsiella. RNAseq analysis was performed to study comparative gene expression.
ORGANISM(S): Homo sapiens 
2025-03-02 | E-MTAB-14744 | biostudies-arrayexpress
MetabolomicsPhysiological, Transcriptomic, and Metabolomic Insights into Ammonia-Nitrogen Stress in the Hepatopancreas of Litopenaeus vannamei Acclimated to Low Salinity
High ammonia nitrogen stress markedly decreases the survival rate of Litopenaeus vannamei under low-salinity conditions. Nevertheless, most available studies have primarily focused on the ammonia nitrogen response of small-sized shrimp under single-stressor exposure or normal seawater salinity. The ...
2026-08-13 | MTBLS14736 | MetaboLights
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