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TranscriptomicsEndothelial DNA methalytion signature in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a severe and incurable pulmonary vascular disease. One of the primary origins of PAH is pulmonary endothelial dysfunction leading to vasoconstriction, aberrant angiogenesis and smooth muscle cell proliferation, endothelial-to-mesenchymal transition, thrombosi...
ORGANISM(S): Homo sapiens 
2016-07-15 | E-GEOD-84395 | biostudies-arrayexpress
Transcriptomics1918 pandemic influenza virus and pneumococcus co-infection results in activation of coagulation and widespread pulmonary microvascular thrombosis in mice and humans
To study the effects of secondary bacterial infection during 1918 pandemic H1N1 influenza virus infection, BALB/c mice were inoculated with the fully reconstructed 1918 influenza virus followed by inoculation with pneumococcus 72h later. To study the effects of secondary bacterial infection during 1...
ORGANISM(S): Mus musculus 
2015-09-20 | E-GEOD-70445 | biostudies-arrayexpress
UnknownPulmonary thrombosis in Covid-19: before, during and after hospital admission.
Not available
S-EPMC7775738 | biostudies-literature
ProteomicsAbsence of COVID-19-associated Changes in Coagulation and Thrombosis in the Ferret Model
Many patients who are diagnosed with coronavirus disease 2019 (COVID-19) suffer from venous thromboembolic complications despite the use of stringent anticoagulant prophylaxis. Studies on the exact mechanism(s) underlying thrombosis in COVID-19 are limited as animal models commonly used to study ven...
ORGANISM(S): Homo sapiens (Human) Mustela putorius furo (European domestic ferret) (Mustela furo) 
2022-07-19 | PXD027582 | Pride
Covid-19 Mass spectrometry Ferrets Thrombosis Proteomics 
UnknownAbsence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model.
Not available
S-EPMC8690567 | biostudies-literature
UnknownPulmonary Thrombosis and Thromboembolism in COVID-19.
Not available
S-EPMC8213519 | biostudies-literature
UnknownDynamic vascular changes in chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy.
Not available
S-EPMC7645796 | biostudies-literature
TranscriptomicsGene expression analysis of pulmonary artery in a rabbit model of pulmonary thromboembolism
Acute pulmonary thromboembolism (PTE) refers to the obstruction of the pulmonary artery or its branches by thrombus. Recent studies suggest that PTE-induced endothelium injury is the major physiological consequence of PTE, and PTE-induced endothelium injury can be used to stratify disease severity....
ORGANISM(S): Oryctolagus cuniculus 
2016-07-23 | E-GEOD-84738 | biostudies-arrayexpress
UnknownClinical, laboratory and immunohistochemical characterization of in situ pulmonary arterial thrombosis in fatal COVID-19.
Not available
S-EPMC9481474 | biostudies-literature
UnknownPulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension Secondary to Expanded Polytetrafluoroethylene Valved Pulmonary Conduit Thrombosis.
Not available
S-EPMC11912009 | biostudies-literature
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