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ProteomicsZC3H11A interacts with PABPN1 and alters polyadenylation of viral transcripts
Nuclear mRNA metabolism is regulated by multiple proteins, which either directly bind to RNA or form multi-protein complexes. The RNA-binding protein ZC3H11A is involved in nuclear mRNA export, and NF-κB signaling and is essential during mouse embryo development. Furthermore, previous studies have s...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042238 | Pride
Zinc finger protein Pabpn1 Zc3h11a Adenovirus Polyadenylation 
ProteomicsComplex regulation of mitochondrial signaling by human adenovirus
The controlled release of mitochondrial content has emerged as a key step in mitochondrial signaling. Particularly the release of mitochondrial DNA (mtDNA) into the cytosol has been shown to activate interferon beta (IFN-β) gene expression to execute the innate immune response. In this report, we sh...
ORGANISM(S): Homo sapiens (Human) 
2024-05-27 | PXD043440 | Pride
Mtdna Sting Pvi Cgas Had5v Mitochondria 
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