Purine act as building block for DNA and RNA, provide cellular energy and signaling, and can generate cofactors such as NADH and coenzyme A. Purine de novo synthesis pathway begins with amino acids, ribose 5-phosphate, CO2 and NH3 with 6 enzymes and 10 enzymatic steps to convert PRPP to IMP. In prev...
This data supports a publication on the PTM status of purinosome proteins transiently expressed in HEK293 cells under +/-purine supplementation cell culture conditions.
