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ProteomicsThe Role of FASN in bladder cancer
To dissect the mechanistic interplay between fatty acid metabolism and cigarette smoke–induced signaling in bladder cancer, we employed a proteomics analysis xenograft tumors derived from the UMUC3 with either stable FASN knockdown (KD) or control shRNA, with and without cigarette smoke. We performe...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-06-15 | PXD068785 | Pride
Proteomics Fasn Cigarette smoke Bladder cancer 
UnknownLiver receptor homolog-1 is a critical determinant of methyl-pool metabolism.

Unlabelled

Balance of labile methyl groups (choline, methionine, betaine, and folate) is important for normal liver function. Quantitatively, a significant use of labile methyl groups is in the production of phosphatidylcholines (PCs), which are ligands for the nuclear liver receptor homolog...
S-EPMC5662191 | biostudies-literature
ProteomicsLabel-free global proteome profiling of European American and African American bladder tumor patients.
Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared to their European American (EA) counterparts, but the molecular mechanism underlying differences are unknown. . Thus, we performed proteomics analysis of AA and EA BLCA and identified higher mitochondrial OXPHOS spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-08 | MSV000095559 | MassIVE
Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
GenomicsMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
There is a critical need to improve our understanding of the pathogenesis of -melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also underwent whole-exome sequencing, T-cell receptor se...
EGAS00001003672 | EGA
GenomicsImmune and Metabolic Features of Brain Metastases Melanoma (Cancer Discovery) Data Access Committee
Data Access Committee EGAC00001001216
EGAC00001001216 | EGA
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