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ProteomicsIdentification of formaldehyde-induced DNA-protein crosslinks by PxP-MS
Compromised enzymatic actions, reactive metabolites, and various chemotherapeutics cause toxic covalent DNA-protein crosslinks (DPCs). Failure to repair DPCs results in genomic instability, premature aging, and tumorigenesis. However, understanding the principles underlying DPC formation and repair ...
ORGANISM(S): Homo sapiens (Human) 
2023-01-20 | PXD026654 | Pride
Formaldehyde Pxp Dna-protein crosslinks Sprtn 
UnknownCo-creating and hosting PxP: a conference about patient engagement in research for and by patient partners.
Not available
S-EPMC11287933 | biostudies-literature
ProteomicsCSB promotes transcription-coupled repair of DNA-protein crosslinks
PxP-MS (Purification of x-linked Proteins coupled to Mass Spectrometry) was used to assess the role of CSB in DNA-protein crosslink repair. The CSB protein is a sensor that can detect stalled RNA polymerases at sites of DNA damage, thereby triggering transcription-coupled repair mechanisms. DPCs wer...
ORGANISM(S): Homo sapiens (Human) 
2024-02-15 | PXD047668 | Pride
Cockayne syndrome Formaldehyde Dna damage repair Dna-protein crosslinks Csb 
UnknownSynthesis and reactivity of a PCcarbeneP cobalt(i) complex: the missing link in the cobalt PXP pincer series (X = B, C, N).
Not available
S-EPMC6240806 | biostudies-literature
UnknownDifferential Profiles of Gut Microbiota and Metabolites Associated with Host Shift of Plutella xylostella.
Not available
S-EPMC7504026 | biostudies-literature
UnknownSPRTN patient variants cause global-genome DNA-protein crosslink repair defects.
Not available
S-EPMC9867749 | biostudies-literature
UnknownStatistical Analysis of SSMIS Sea Ice Concentration Threshold at the Arctic Sea Ice Edge during Summer Based on MODIS and Ship-Based Observational Data.
Not available
S-EPMC5948642 | biostudies-literature
ProteomicsExtensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016465 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
UnknownThe association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5.
Not available
S-EPMC10053439 | biostudies-literature
UnknownStructural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4.
Not available
S-EPMC6161044 | biostudies-literature
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