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ProteomicsAn isobaric quantitative crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and protein complexes
Experimental determination of protein conformational states is crucial to understand the mechanism of protein function and how function is altered in disease. We introduce a novel, simple and compact, isobaric crosslinker design for studying conformational and structural changes using quantitative m...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-11-13 | PXD035939 | Pride
Conformational change. Qclms Q2linkers Qlinker Isobaric 
ProteomicsIsobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes
Dynamic conformational and structural changes in proteins and protein complexes play a central and ubiquitous role in the regulation of protein function, yet it is very challenging to study these changes, especially for large protein complexes, under physiological conditions. Here we introduce a nov...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-11-13 | PXD056825 | Pride
Isobaric crosslinkers Qclms Conformational changes Quantitative crosslinking mass spectrometry 
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