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UnknownTP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.
Not available
S-EPMC5815403 | biostudies-literature
ProteomicsDefective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation
Proteomics and phosphoproteomics analyses of two human pluripotent stem cell (hPSC) lines with stable insulin receptor knock down. 6-plex TMT-based strategy was applied to compare control versus insulin receptor (IR) knockdown (n=3 replicates for each condition) for each cell lines (CHB8 and H9). D...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-16 | MSV000085298 | MassIVE
UnknownVeterans with Gulf War Illness exhibit distinct respiratory patterns during maximal cardiopulmonary exercise.
Not available
S-EPMC6850551 | biostudies-literature
UnknownUp-regulation of DDIT4 predicts poor prognosis in acute myeloid leukaemia.
Not available
S-EPMC6933361 | biostudies-literature
ProteomicsDeKinomics pulse-chases kinase functions in living cells
Cellular context is crucial for understanding the complex and dynamic kinase functions in health and disease. Systematic dissection of kinase-mediated cellular processes requires rapid and precise stimulation (“pulse”) of a kinase of interest, as well as global and in-depth characterization (“chase”...
ORGANISM(S): Homo Sapiens 
2023-10-07 | PXD039316 |
TranscriptomicsTranscription profiling of mouse models or Parkinsons disease reveal miRNAs and codon usage regulate striatal gene and protein expression
The molecular mechanisms underlying the changes in the nigrostriatal pathway in Parkinson’s disease (PD) are not completely understood. Here we use microarrays and mass spectrometry to study the transcriptomic and proteomic changes in the striatum of two mouse models of PD induced by distinct neu...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-8030 | biostudies-arrayexpress
ProteomicsMultimodal measurement of the transcriptome and proteome in G2/M arrested single cells using nanoSPLITS
Single-cell proteomic data from RO-3306 treated alveolar type II epithelial cells (C10) and untreated C10 cells. Cells were sorted using cellenONE onto several nanoSPLITS chips. Cell lysates were then split for parallel RNAseq and proteomic analysis. For proteomics recovery experiment where both chi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-12-02 | MSV000090828 | MassIVE
ProteomicsMultimodal measurement of the transcriptome and proteome from dissociated human pancreatic islet cells using nanoSPLITS
Human pancreatic islets from two human donors (Prodo Laboratories) were acquired and cultured for 24 hr in pancreatic islet media (PIMS, Prodo Laboratories). Single cells were dissociated with TrypLE for ~15-30 minutes, washed with PBS, stained with Calcein-AM/propidium iodide, and sorted onto nanoS...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-07 | MSV000093330 | MassIVE
UnknownThe dynamic conformational landscape of the protein methyltransferase SETD8.
Not available
S-EPMC6579520 | biostudies-literature
UnknownGenetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Not available
S-EPMC6284793 | biostudies-literature
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