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MetabolomicsUrine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
ProteomicsHuman normal and peritumor liver tissues LC-MSMS
The tumor microenvironment (TME) plays an important role in tumorigenesis1. The TME is usually studied in tumor tissue and in relation to tumor progression2,3, which can limit understanding of how the TME is involved in processes associated with initial tumorigenesis as well as tumor recurrence and ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD023118 | Pride
Human Lc-msms Hcc Liver 
TranscriptomicsTracing pluripotency of human early embryos and embryonic stem cells by single cell RNA-seq
Find the casual relationship between gene expression network and cellular phenotype at single cell resolution. We collected donated human pre-implatation embryos, and the embryonic stem cells derived from them, isolate individual cells, prepared single cell cDNAs, and sequenced them by HiSeq2000. Th...
ORGANISM(S): Homo sapiens 
2013-08-10 | E-GEOD-36552 | biostudies-arrayexpress
TranscriptomicsThe DNA methylation landscape of human early embryos
Our data provided a genome-wide DNA methylation landscape of human early development embryos, including human MII oocytes, sperm, zygotes, 2-cell to 8-cell embryos, morula, blastocyst and postimplantation embryos at single base resolution. In total, 44 samples including biological and technical repl...
ORGANISM(S): Homo sapiens 
2014-07-22 | E-GEOD-49828 | biostudies-arrayexpress
UnknownDevelopment and trend in the field of valvular heart disease in China: an analysis based on the National Natural Science Foundation of China.
Not available
S-EPMC7210194 | biostudies-literature
UnknownDABCO-catalyzed Knoevenagel condensation of aldehydes with ethyl cyanoacetate using hydroxy ionic liquid as a promoter.
Not available
S-EPMC9085423 | biostudies-literature
UnknownMicrobial Diversity and Volatile Flavor Compounds in Tibetan Flavor Daqu.
Not available
S-EPMC9858000 | biostudies-literature
GenomicsWhole-genome analysis of 5-hydroxymethylcytosines and 5-methylcytosines at base resolution in human brain
5-hydroxymethylcytosines (5hmC) is particularly abundant in mammalian brain with little-known functions. Here we present the first genome-wide and single-base-resolution maps of 5hmC and 5mC in human brain by combined application of TAB-Seq and MethylC-Seq. We report that the majority of modified cy...
ORGANISM(S): Homo sapiens 
2014-02-14 | E-GEOD-46710 | biostudies-arrayexpress
UnknownCharacterization of a Novel <i>Lentzea</i> Species Isolated from the Kumtagh Desert and Genomic Insights into the Secondary Metabolite Potential of the Genus.
Not available
S-EPMC12300779 | biostudies-literature
UnknownTissue Type: A Crucial Factor Influencing the Fungal Diversity and Communities in Sichuan Pork Bacon.
Not available
S-EPMC8268000 | biostudies-literature
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