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MetabolomicsExtracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
The accumulation of acidic metabolic waste products within the tumor microenvironment profoundly inhibits effector functions of tumor-infiltrating lymphocytes (TILs). However, it is unclear whether extracellular-acidosis impacts T cell metabolic fitness and differentiation status. Here, we surprisin...
2023-01-17 | MTBLS6661 | MetaboLights
Unknown<i>Lycorine hydrochloride</i> Suppresses the Proliferation and Invasion of Esophageal Cancer by Targeting TRIM22 and Inhibiting the JAK2/STAT3 and Erk Pathways.
Not available
S-EPMC11898953 | biostudies-literature
UnknownInfiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals.
Not available
S-EPMC5055306 | biostudies-literature
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
UnknownExtracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.
Not available
S-EPMC9970874 | biostudies-literature
UnknownCirculating senescent angiogenic T cells are linked with endothelial dysfunction and systemic inflammation in hypertension.
Not available
S-EPMC8048736 | biostudies-literature
UnknownProtein catenation potentiates antitumor activity of malaria VAR2CSA navigation CAR-T cells in a mouse model of hematological malignancies.
Not available
S-EPMC12636975 | biostudies-literature
UnknownFunctionally impaired follicular helper T cells induce regulatory B cells and CD14+ human leukocyte antigen-DR- cell differentiation in non-small cell lung cancer.
Not available
S-EPMC6272090 | biostudies-literature
UnknownThe diagnostic effect of integrated visual and auditory continuous performance and event-related potentials in ADHD.
Not available
S-EPMC11558357 | biostudies-literature
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