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BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
selecte tissues from seven patients with pancreatic cancer and then investigated the Khib modification in them by using proteomics technology.
ORGANISM(S): Homo sapiens (Human) 
2022-12-02 | PXD029817 | Pride
HEK293T cells were ectopically expressing Flag tagged p62 (p62 group) or empty vectors (Control group) for 48h, cell lysates were incubated with anti-Flag affinity gels, and co-immunoprecipitates were subjected to trypsin digestion followed by mass spectrometry analysis. Peptides were separated by t...
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD062511 | Pride
HEK293T cells were ectopically expressing Flag tagged p62 (p62 group) or empty vectors (Control group) for 48h, cell lysates were incubated with anti-Flag affinity gels, and co-immunoprecipitates were subjected to trypsin digestion followed by mass spectrometry analysis. Peptides were separated by t...
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD061794 | Pride
In E. coli, the pACYC-HA-Ub-E1 (UBA1)-UbcH5A-RNF126 and pET-22b-MIDN-His₆ plasmids were co-transformed. After IPTG induction to express all proteins required for ubiquitination, His-tagged MIDN was enriched with Ni-NTA resin and subjected to mass-spectrometric mapping of its ubiquitin-modified sites...
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD069387 | Pride
The Notch signaling is an evolutionarily conserved signal transduction cascade that plays essential roles in a variety of developmental processes. In this study, we examined the mib mutants for defects in pancreas development using in situ hybridization and GFP expression analysis of pancreas-specif...
ORGANISM(S): Danio rerio 
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