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MetabolomicsImpact of in vitro hormone treatments on the bibenzyl production of Radula complanata (Untargeted metabolomics)

Bibenzyls are a specialized metabolite class found throughout the plant kingdom. One of the most prolific producers of bibenzyls are liverworts, specifically plants of the Radula genera. These plants possess an incredible diversity of bibenzyls, prenylated bibenzyls and a few (bis)bibenz...

2024-01-10 | MTBLS3563 | MetaboLights
ProteomicsProteomic dataset for clematis in respose to heat stress
This project presents the raw data about pretomic of two clematis seedings in response to heat stress at 38 oC for 3 h
ORGANISM(S): Clematis chinensis 
2020-06-04 | PXD018192 | Pride
Clematis Proteomic Ros Heat stress 
ProteomicsEGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association
EGF is one of the most well-characterized growth factors and plays a crucial role in cell proliferation and differentiation. EGFR has been extensively explored as a therapeutic target against multiple types of cancers, such as lung cancer and glioblastoma. Recent studies have established a connectio...
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD031593 | Pride
Epidermal growth factor (egf) Phosphotyrosine binding protein O-glcnacylation Pyruvate kinase m2 (pkm2) Phosphorylation O-glcnac transferase (ogt) 
MetabolomicsHost Tree and Geography Induce Metabolic Shifts in the Epiphytic Liverwort Radula complanata
Bryophytes are prolific producers of unique, specialized metabolites that are not found in other plants. As many of these unique natural products are potentially interesting, for example, pharmacological use, variations in the production regarding ecological or environmental conditions have not ofte...
2026-01-29 | MTBLS6740 | MetaboLights
ProteomicsPKM2 functions as a histidine kinase to phosphorylate PGAM1 to increase glycolysis shunts in cancer-Cellular lipid level assessment
Phosphoglycerate mutase 1 (PGAM1) is a key node enzyme that diverts the metabolic reactions from glycolysis into its shunts to support macromolecule biosynthesis for rapid and sustainable cell proliferation. It is prevalent that PGAM1 activity is upregulated in various tumors; however, the underlyin...
ORGANISM(S): Homo sapiens (Human) 
2024-03-21 | PXD049310 | Pride
Glycolysis shunts Pyruvate kinase m2 (pkm2) Histidine kinase Phosphorylation Phosphoglycerate mutase 1 (pgam1) 
ProteomicsPKM2 functions as a histidine kinase to phosphorylate PGAM1 to increase glycolysis shunts in cancer
Phosphoglycerate mutase 1 (PGAM1) is a key-node enzyme that diverts the metabolic intermediates from glycolysis into its shunts to support macromolecule biosynthesis for rapid and sustainable cell proliferation. It is prevalent that PGAM1 activity is upregulated in various tumors; however, the under...
ORGANISM(S): Homo sapiens (Human) 
2024-03-21 | PXD049235 | Pride
Glycolysis shunts Pyruvate kinase m2 (pkm2) Histidine kinase Phosphorylation Phosphoglycerate mutase 1 (pgam1) 
TranscriptomicsDynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging- Related Transcriptional Networks
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-28641 | biostudies-arrayexpress
TranscriptomicsRegulatory role of SrrAB two-component system in Staphylococcus epidermidis growth and biofilm formation
Biofilm formation is considered the most important factor involved in pathogenicity of Staphylococcus epidermidis.We investigated the role of two-component signal transduction system (TCS) srrAB, which was up-regulated under micro-aerobic condition, in the growth and biofilm formation of S. epidermi...
ORGANISM(S): Staphylococcus epidermidis 
2014-11-21 | E-GEOD-47101 | biostudies-arrayexpress
ProteomicsProteomic Characterization of Polymicrobial Biofilms in Human Urine
When Proteus mirabilis, Enterococcus faecalis, and Escherichia coli are co-cultured in human urine, they form biofilms with increased biomass. This increase in biomass is due to a rise in the total protein content of the biofilm rather than other components, such as carbohydrates or nucleic acids. T...
ORGANISM(S): Escherichia coli Proteus mirabilis HI4320 Bacteria Enterococcus faecalis (Streptococcus faecalis) 
2026-08-24 | PXD074670 | Pride
Proteomics Lc-ms Enterococcus faecalis Proteus mirabilis Biofilm Escherichia coli 
MetabolomicsModerate salinity restricts the transformation depth of norfloxacin by halotolerant Chlorella sp. AMC-2: Physiological adaptation and metabolic reprogramming
Despite increasing application of microalgae for antibiotic-contaminated aquaculture wastewater treatment, how salinity regulates antibiotic transformation depth and cellular adaptation remains unclear. This study combined salinity-gradient cultivation, process partitioning, transformation-product p...
2026-10-01 | MTBLS15888 | MetaboLights
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